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Jacopo C DiFrancesco

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Recent Articles
11.
Pikija S, Pretnar-Oblak J, Frol S, Malojcic B, Gattringer T, Rak-Frattner K, et al.
Int J Stroke . 2023 Sep; 19(3):314-321. PMID: 37700397
Background: The transmission of amyloid β (Aβ) in humans leading to iatrogenic cerebral amyloid angiopathy (iCAA) is a novel concept with analogies to prion diseases. However, the number of published...
12.
Damavandi P, Pasini F, Fanella G, Cereda G, Mainini G, DiFrancesco J, et al.
Brain Sci . 2023 Feb; 13(2). PMID: 36831869
Brain tumor-related epilepsy (BTRE) is a common comorbidity in patients with brain neoplasms and it may be either the first symptom or develop after the tumor diagnosis. Increasing evidence suggests...
13.
Castellotti B, Canafoglia L, Freri E, Tappata M, Messina G, Magri S, et al.
Epilepsia Open . 2023 Jan; 8(2):645-650. PMID: 36719163
Variants of SEMA6B have been identified in an increasing number of patients, often presenting with progressive myoclonus epilepsy (PME), and to lesser extent developmental encephalopathy, with or without epilepsy. The...
14.
Beghi E, Giussani G, Costa C, DiFrancesco J, Dhakar M, Leppik I, et al.
Epilepsia . 2023 Jan; 64(3):586-601. PMID: 36625133
In an aging world, it is important to know the burden of epilepsy affecting populations of older persons. We performed a selective review of epidemiological studies that we considered to...
15.
Damavandi P, Storti B, Fabin N, Bianchi E, Ferrarese C, DiFrancesco J
Epilepsia . 2022 Dec; 64(2):500-510. PMID: 36515439
Objective: Cerebral amyloid angiopathy (CAA) is a major cause of spontaneous intracranial hemorrhage in older adults. Epilepsy represents a possible sequela of the disease. To date, studies on epilepsy in...
16.
Piccenna L, ODwyer R, Leppik I, Beghi E, Giussani G, Costa C, et al.
Epilepsia . 2022 Oct; 64(3):567-585. PMID: 36266921
Older adults represent a highly heterogeneous population, with multiple diverse subgroups. Therefore, an individualized approach to treatment is essential to meet the needs of each unique subgroup. Most comparative studies...
17.
Gasparini S, Ferlazzo E, Neri S, Cianci V, Iudice A, Bisulli F, et al.
Epilepsia Open . 2022 Sep; 7(4):687-696. PMID: 36082380
Objective: Perampanel (PER) is indicated as adjunctive antiseizure medication (ASM) in adolescents and adults with epilepsy. Data from clinical trials show good efficacy and tolerability, while limited information is available...
18.
Piazza F, Caminiti S, Zedde M, Presotto L, DiFrancesco J, Pascarella R, et al.
Neurology . 2022 Aug; 99(12):e1265-e1277. PMID: 35940900
Background And Objectives: Amyloid-related imaging abnormalities suggestive of vasogenic edema or sulcal effusion (ARIA-E) are the most common adverse events complicating Alzheimer disease (AD) immunotherapy with anti-β-amyloid (Aβ) monoclonal antibodies....
19.
Mosca I, Rivolta I, Labalme A, Ambrosino P, Castellotti B, Gellera C, et al.
Front Pharmacol . 2022 Jun; 13:872645. PMID: 35770094
Pathogenic variants in KCNQ2 encoding for Kv7.2 potassium channel subunits have been found in patients affected by widely diverging epileptic phenotypes, ranging from Self-Limiting Familial Neonatal Epilepsy (SLFNE) to severe...
20.
DiFrancesco J, Labate A, Romoli M, Chipi E, Salvadori N, Galimberti C, et al.
Front Neurol . 2022 Apr; 13:851897. PMID: 35359649
Epilepsy is classically considered a childhood disease. However, it represents the third most frequent neurological condition in the elderly, following stroke, and dementia. With the progressive aging of the general...