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Jacopo Baglieri

Explore the profile of Jacopo Baglieri including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 551
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Recent Articles
1.
Su H, Yang F, Fu R, Trinh B, Sun N, Liu J, et al.
Nature . 2023 Mar; 615(7953):E24. PMID: 36882540
No abstract available.
2.
Su H, Yang F, Fu R, Trinh B, Sun N, Liu J, et al.
Nature . 2022 Oct; 610(7931):366-372. PMID: 36198801
Pancreatic ductal adenocarcinoma (PDAC) is a highly desmoplastic, aggressive cancer that frequently progresses and spreads by metastasis to the liver. Cancer-associated fibroblasts, the extracellular matrix and type I collagen (Col...
3.
Nishio T, Koyama Y, Liu X, Rosenthal S, Yamamoto G, Fuji H, et al.
Proc Natl Acad Sci U S A . 2021 Jul; 118(29). PMID: 34253615
We investigated the role of mesothelin (Msln) and thymocyte differentiation antigen 1 (Thy1) in the activation of fibroblasts across multiple organs and demonstrated that Msln mice are protected from cholestatic...
4.
Baglieri J, Zhang C, Liang S, Liu X, Nishio T, Rosenthal S, et al.
Am J Pathol . 2021 Jun; 191(9):1564-1579. PMID: 34119473
Although hepatocellular cancer (HCC) usually occurs in the setting of liver fibrosis, the causal relationship between liver fibrosis and HCC is unclear. in vivo and in vitro models of HCC...
5.
Berumen J, Baglieri J, Kisseleva T, Mekeel K
WIREs Mech Dis . 2020 Jul; 13(1):e1499. PMID: 32713091
Liver fibrosis is a clinically significant finding that has major impacts on patient morbidity and mortality. The mechanism of fibrosis involves many different cellular pathways, but the major cell type...
6.
Liu X, Rosenthal S, Meshgin N, Baglieri J, Musallam S, Diggle K, et al.
Hepatol Commun . 2020 Apr; 4(4):606-626. PMID: 32258954
Alcoholic liver disease (ALD) is a leading cause of cirrhosis in the United States, which is characterized by extensive deposition of extracellular matrix proteins and formation of a fibrous scar....
7.
Xu J, Ma H, Liu X, Rosenthal S, Baglieri J, McCubbin R, et al.
JCI Insight . 2020 Feb; 5(3). PMID: 32051339
Chronic alcohol abuse has a detrimental effect on the brain and liver. There is no effective treatment for these patients, and the mechanism underlying alcohol addiction and consequent alcohol-induced damage...
8.
Dhar D, Baglieri J, Kisseleva T, Brenner D
Exp Biol Med (Maywood) . 2020 Jan; 245(2):96-108. PMID: 31924111
No abstract available.
9.
Nishio T, Hu R, Koyama Y, Liang S, Rosenthal S, Yamamoto G, et al.
J Hepatol . 2019 May; 71(3):573-585. PMID: 31071368
Background & Aims: Chronic liver injury often results in the activation of hepatic myofibroblasts and the development of liver fibrosis. Hepatic myofibroblasts may originate from 3 major sources: hepatic stellate...
10.
Baglieri J, Brenner D, Kisseleva T
Int J Mol Sci . 2019 Apr; 20(7). PMID: 30959975
Hepatocellular carcinoma (HCC) is one of the most aggressive types of cancer and lacks effective therapeutic approaches. Most HCC develops in the setting of chronic liver injury, hepatic inflammation, and...