Jacobus P J Ungerer
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Explore the profile of Jacobus P J Ungerer including associated specialties, affiliations and a list of published articles.
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96
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1066
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Recent Articles
1.
Giuliani K, Nag P, Adams B, Wang X, Hong S, Grivei A, et al.
Cell Death Dis
. 2025 Jan;
16(1):61.
PMID: 39890773
Hypoxia and interleukin (IL)-1β are independent mediators of tubulointerstitial fibrosis, the histological hallmark of chronic kidney disease (CKD). Here, we examine how hypoxia and IL-1β act in synergy to augment...
2.
Alexander K, Tseng H, Lao H, Girard D, Barbier V, Ungerer J, et al.
Cell Rep Med
. 2024 Dec;
5(12):101849.
PMID: 39657663
Why severe injury to the central nervous system (CNS) triggers the development of large neurogenic heterotopic ossifications (NHOs) within periarticular muscles remains unknown. We report that spinal cord injury (SCI)...
3.
Chai M, Tu Q, Cotta M, Bauer M, Balch R, Okafor C, et al.
Intensive Care Med
. 2024 Apr;
50(5):810.
PMID: 38563901
No abstract available.
4.
Chai M, Tu Q, Cotta M, Bauer M, Balch R, Okafor C, et al.
Intensive Care Med
. 2024 Mar;
50(4):539-547.
PMID: 38478027
Purpose: Early recognition and effective treatment of sepsis improves outcomes in critically ill patients. However, antibiotic exposures are frequently suboptimal in the intensive care unit (ICU) setting. We describe the...
5.
Wang X, Kim C, Adams B, Wilkinson R, Hill M, Shah A, et al.
Redox Biol
. 2024 Jan;
70:103042.
PMID: 38244399
Hypoxia is the key pathobiological trigger of tubular oxidative stress and cell death that drives the transition of acute kidney injury (AKI) to chronic kidney disease (CKD). The mitochondrial-rich proximal...
6.
Cameron C, Vuong K, McWhinney B, Zournazi A, Manzanero S, Warren J, et al.
Drug Alcohol Rev
. 2023 Sep;
42(7):1796-1806.
PMID: 37703216
Introduction: The health impact from alcohol is of recognised concern, from acute intoxication as well as increased risk of chronic health issues over time. Identifying factors associated with higher alcohol...
7.
Chai M, Roberts J, Kelly C, Ungerer J, McWhinney B, Lipman J, et al.
Anaesth Crit Care Pain Med
. 2023 Aug;
42(6):101296.
PMID: 37579945
Introduction: Broad-spectrum antibiotics such as beta-lactams and vancomycin are frequently used to treat critically ill patients, however, a significant number do not achieve target exposures. Therapeutic drug monitoring (TDM) combined...
8.
Development of epistatic YES and AND protein logic gates and their assembly into signalling cascades
Guo Z, Smutok O, Ayva C, Walden P, Parker J, Whitfield J, et al.
Nat Nanotechnol
. 2023 Jul;
18(11):1327-1334.
PMID: 37500780
The construction and assembly of artificial allosteric protein switches into information and energy processing networks connected to both biological and non-biological systems is a central goal of synthetic biology and...
9.
10.
Pretorius C, Wilgen U, Klingberg S, Zournazi A, Sanders L, Ungerer J
Clin Chem Lab Med
. 2023 Apr;
61(10):1841-1849.
PMID: 37078204
Objectives: We tested the hypothesis that the free-β subunit (βhCG) is diagnostically more sensitive with total hCG assays (hCGt) not detecting all tumours secreting βhCG. The effects of sex, age,...