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Jacobo Mintzer

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Articles 45
Citations 1650
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Recent Articles
1.
Sankhe K, Tumati S, Perin J, Rivet L, Vieira D, Rosenberg P, et al.
Int Psychogeriatr . 2025 Mar; 37(2):100012. PMID: 40086910
Background: Previous trials have shown improvements in both apathy and cognition with methylphenidate (MPH). Objectives: To assess whether changes in apathy correlated with changes in cognition in the Apathy in...
2.
Borson S, Au R, Chodos A, Gandy S, Jain H, Alagor A, et al.
Alzheimers Dement (Amst) . 2025 Mar; 17(1):e70095. PMID: 40071061
Highlights: Blood-based biomarkers can streamline the identification of AD in primary care.Future biomarker-enabled diagnostic care pathways will leverage digital assessments.Education, data generation, and policy advocacy are vital to encourage BBBM...
3.
Wang L, Hu W, Dong F, Sheng C, Wu J, Han Y, et al.
Geroscience . 2025 Jan; PMID: 39888585
Brain network dynamics have been extensively explored in patients with subjective cognitive decline (SCD). However, these studies are susceptible to individual differences, scanning parameters, and other confounding factors. Therefore, how...
4.
Long C, Fritts A, Broadway J, Brawman-Mintzer O, Mintzer J
J Clin Med . 2025 Jan; 14(2. PMID: 39860337
: The goal of this commentary is to highlight several key components of the inflammatory process as it relates to amyloid toxicity in Alzheimer's disease (AD), including the role of...
5.
Tumati S, Herrmann N, Perin J, Rosenberg P, Lerner A, Mintzer J, et al.
Int Psychogeriatr . 2024 Sep; 36(12):1232-1244. PMID: 39297292
Objectives: Among participants with Alzheimer's disease (AD) we estimated the minimal clinically important difference (MCID) in apathy symptom severity on three scales. Design: Retrospective anchor- and distribution-based analyses of change...
6.
Zivko C, Sagar R, Xydia A, Lopez-Montes A, Mintzer J, Rosenberg P, et al.
Mol Psychiatry . 2024 Jun; 29(11):3644-3652. PMID: 38840027
Alzheimer's disease (AD) is the most common cause of dementia, and the gradual deterioration of brain function eventually leads to death. Almost all AD patients suffer from neuropsychiatric symptoms (NPS),...
7.
Eyre H, Stirland L, Jeste D, Reynolds 3rd C, Berk M, Ibanez A, et al.
Am J Geriatr Psychiatry . 2023 Oct; 31(12):1017-1031. PMID: 37798224
This position statement of the Expert Panel on Brain Health of the American Association for Geriatric Psychiatry (AAGP) emphasizes the critical role of life course brain health in shaping mental...
8.
Clark E, Perin J, Herrmann N, Brawman-Mintzer O, Lanctot K, Lerner A, et al.
Alzheimers Dement (N Y) . 2023 Aug; 9(3):e12403. PMID: 37538343
Introduction: Methylphenidate has been shown to improve apathy in patients with Alzheimer's disease (AD). The authors evaluated the impact of methylphenidate on neuropsychiatric symptoms (NPS) of AD, excluding apathy, using...
9.
Lanctot K, Rivet L, Tumati S, Perin J, Sankhe K, Vieira D, et al.
Am J Geriatr Psychiatry . 2023 Jun; 31(12):1077-1087. PMID: 37385898
Objective: The Apathy in Dementia Methylphenidate Trial 2 (ADMET 2) found that methylphenidate was effective in treating apathy with a small-to-medium effect size but showed heterogeneity in response. We assessed...
10.
Lanctot K, Chen C, Mah E, Kiss A, Li A, Shade D, et al.
Int Psychogeriatr . 2023 Apr; 35(11):664-672. PMID: 37066690
Background: This paper used data from the Apathy in Dementia Methylphenidate Trial 2 (NCT02346201) to conduct a planned cost consequence analysis to investigate whether treatment of apathy with methylphenidate is...