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Jacobo de Una-Alvarez

Explore the profile of Jacobo de Una-Alvarez including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 357
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Recent Articles
11.
Azarang L, Scheike T, de Una-Alvarez J
Stat Med . 2017 Feb; 36(12):1964-1976. PMID: 28238225
In this work, we present direct regression analysis for the transition probabilities in the possibly non-Markov progressive illness-death model. The method is based on binomial regression, where the response is...
12.
Pego-Reigosa J, Lois-Iglesias A, Rua-Figueroa I, Galindo M, Calvo-Alen J, de Una-Alvarez J, et al.
Rheumatology (Oxford) . 2016 Mar; 55(7):1243-50. PMID: 27018057
Objectives: To identify patterns (clusters) of damage manifestations within a large cohort of SLE patients and evaluate the potential association of these clusters with a higher risk of mortality. Methods:...
13.
Rodriguez-Girondo M, de Una-Alvarez J
Stat Med . 2016 Mar; 35(20):3549-62. PMID: 26990971
Markov three-state progressive and illness-death models are often used in biomedicine for describing survival data when an intermediate event of interest may be observed during the follow-up. However, the usual...
14.
Castro-Conde I, Dohler S, de Una-Alvarez J
Stat Methods Med Res . 2015 Aug; 26(5):2356-2375. PMID: 26265767
The sequential goodness-of-fit (SGoF) multiple testing method has recently been proposed as an alternative to the familywise error rate- and the false discovery rate-controlling procedures in high-dimensional problems. For discrete...
15.
de Una-Alvarez J, Meira-Machado L
Biometrics . 2015 Mar; 71(2):364-75. PMID: 25735883
Multi-state models are often used for modeling complex event history data. In these models the estimation of the transition probabilities is of particular interest, since they allow for long-term predictions...
16.
Castro-Conde I, de Una-Alvarez J
Biom J . 2014 Oct; 57(1):108-22. PMID: 25323102
In the field of multiple comparison procedures, adjusted p-values are an important tool to evaluate the significance of a test statistic while taking the multiplicity into account. In this paper,...
17.
Franco-Pereira A, de Una-Alvarez J
Biom J . 2012 Dec; 55(1):52-67. PMID: 23225621
In this paper, we introduce a new estimator of a percentile residual life function with censored data under a monotonicity constraint. Specifically, it is assumed that the percentile residual life...
18.
Rodriguez-Girondo M, de Una-Alvarez J
Stat Med . 2012 Sep; 31(30):4416-27. PMID: 22975898
Multistate models are useful tools for modeling disease progression when survival is the main outcome, but several intermediate events of interest are observed during the follow-up time. The illness-death model...
19.
de Una-Alvarez J
Stat Appl Genet Mol Biol . 2012 May; 11(3):Article 14. PMID: 22611594
In this paper a correction of SGoF multitesting method for dependent tests is introduced. The correction is based in the beta-binomial model, and therefore the new method is called Beta-...
20.
Rodriguez-Girondo M, de Una-Alvarez J
Biom J . 2012 Apr; 54(2):163-80. PMID: 22522376
The three-state progressive model is a special multi-state model with important applications in Survival Analysis. It provides a suitable representation of the individual's history when an intermediate event (with a...