Jacoba C Graver
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Explore the profile of Jacoba C Graver including associated specialties, affiliations and a list of published articles.
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6
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78
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Recent Articles
1.
Xu S, Jiemy W, van Sleen Y, Westra J, Graver J, van der Geest K, et al.
Rheumatology (Oxford)
. 2025 Mar;
PMID: 40084998
Objective: Giant cell arteritis (GCA) is a systemic vasculitis of large- and medium-sized arteries characterized by granulomatous inflammation and vascular remodelling. Although fibroblasts are the predominant cell type in the...
2.
Graver J, Jiemy W, Altulea D, van Sleen Y, Xu S, van der Geest K, et al.
J Autoimmun
. 2023 Sep;
140:103111.
PMID: 37703805
Objective: The lack of disease-specific autoantibodies in giant cell arteritis (GCA) suggests an alternative role for B-cells readily detected in the inflamed arteries. Here we study the cytokine profile of...
3.
Jiemy W, van Sleen Y, Graver J, Pringle S, Brouwer E, van der Geest K, et al.
Arthritis Rheumatol
. 2023 Apr;
75(10):1812-1818.
PMID: 37057491
Objective: Giant cell arteritis (GCA) affects almost exclusively individuals above 50 years old, suggesting a role of aging-related changes such as cellular senescence in its pathobiology. The kinases p21(WAF1/CIP1) and...
4.
Reitsema R, van der Geest K, Sandovici M, Jiemy W, Graver J, Abdulahad W, et al.
Rheumatology (Oxford)
. 2022 Apr;
62(1):417-427.
PMID: 35460236
Objectives: Evidence from temporal artery tissue and blood suggests involvement of CD8+ T cells in the pathogenesis of GCA, but their exact role is poorly understood. Therefore, we performed a...
5.
Graver J, Abdulahad W, van der Geest K, Heeringa P, Boots A, Brouwer E, et al.
J Autoimmun
. 2021 Jul;
123:102684.
PMID: 34237649
Objective: B-cells are present in the inflamed arteries of giant cell arteritis (GCA) patients and a disturbed B-cell homeostasis is reported in peripheral blood of both GCA and the overlapping...
6.
van Sleen Y, Graver J, Abdulahad W, van der Geest K, Boots A, Sandovici M, et al.
Front Immunol
. 2019 Sep;
10:1981.
PMID: 31507597
Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are inflammatory diseases requiring long-term glucocorticoid treatment. Limited data on dynamics in leukocyte counts before, during and after treatment are available. Leukocyte...
7.
Graver J, Boots A, Haacke E, Diepstra A, Brouwer E, Sandovici M
Front Immunol
. 2019 Feb;
10:83.
PMID: 30761147
Giant cell arteritis (GCA) can be classified into Cranial(C)-GCA and Large Vessel(LV)-GCA. Based on analysis of temporal arteries, GCA is postulated to be T-cell-mediated. Recently, a disturbed B-cell homeostasis was...