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Jacob Mitchell

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Citations 89
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Recent Articles
1.
Guinn S, Perez B, Tandurella J, Ramani M, Lee J, Zabransky D, et al.
bioRxiv . 2025 Jan; PMID: 39829906
Pancreatic ductal adenocarcinoma (PDAC) carries an extremely poor prognosis, in part resulting from cellular heterogeneity that supports overall tumorigenicity. Cancer associated fibroblasts (CAF) are key determinants of PDAC biology and...
2.
Orusa A, Wahlquist A, Lawson D, Riaz O, Mitchell J, Tafesse Y, et al.
J Am Coll Health . 2024 Nov; :1-5. PMID: 39566045
The COVID-19 pandemic has provided the general public with an understanding of scientific processes and health systems surrounding vaccination in real-time. This report assesses responses of college students in a...
3.
Johnson J, Stein-OBrien G, Booth M, Heiland R, Kurtoglu F, Bergman D, et al.
bioRxiv . 2023 Sep; PMID: 37745323
Cells are fundamental units of life, constantly interacting and evolving as dynamical systems. While recent spatial multi-omics can quantitate individual cells' characteristics and regulatory programs, forecasting their evolution ultimately requires...
4.
Davidson S, Yu C, Steiner A, Ebstein F, Baker P, Jarur-Chamy V, et al.
Sci Immunol . 2022 Feb; 7(68):eabi6763. PMID: 35148201
Proteasome dysfunction can lead to autoinflammatory disease associated with elevated type I interferon (IFN-αβ) and NF-κB signaling; however, the innate immune pathway driving this is currently unknown. Here, we identified...
5.
Grygiel-Gorniak B, Tariq H, Mitchell J, Mohammed A, Samborski W
Postgrad Med . 2021 Sep; 133(8):953-963. PMID: 34533099
Background: Relapsing polychondritis (RPC) is a complex immune-mediated systemic disease affecting cartilaginous tissue and proteoglycan-rich organs. The most common and earliest clinical features are intermittent inflammation involving the auricular and...
6.
Lin B, Torreggiani S, Kahle D, Rumsey D, Wright B, Montes-Cano M, et al.
Front Immunol . 2021 Apr; 12:636225. PMID: 33833757
Gain-of-function mutations in cause the monogenic interferonopathy, SAVI, which presents with early-onset systemic inflammation, cold-induced vasculopathy and/or interstitial lung disease. We identified 5 patients (3 kindreds) with predominantly peripheral vascular...
7.
Bhuyan F, de Jesus A, Mitchell J, Leikina E, VanTries R, Herzog R, et al.
Arthritis Rheumatol . 2020 Dec; 73(6):1021-1032. PMID: 33314777
Objective: To identify novel heterozygous LPIN2 mutations in a patient with Majeed syndrome and characterize the pathomechanisms that lead to the development of sterile osteomyelitis. Methods: Targeted genetic analysis and...
8.
Lin B, Berard R, Al Rasheed A, Aladba B, Kranzusch P, Henderlight M, et al.
J Allergy Clin Immunol . 2020 Jul; 146(5):1204-1208.e6. PMID: 32673614
No abstract available.
9.
Saxena S, Mitchell J, Ehsan A, Majnemer A, Shikako-Thomas K
Child Care Health Dev . 2019 Nov; 46(1):132-148. PMID: 31782542
Background: Children and adolescents with neurodevelopmental disabilities may be less well integrated into their community than their peers. Online groups can be particularly accessible for individuals with neurodevelopmental disabilities, as...