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Jacob K Olson

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Articles 11
Citations 325
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Recent Articles
1.
Shelby R, Tengberg N, Conces M, Olson J, Navarro J, Bailey M, et al.
J Invest Surg . 2019 Mar; 33(10):887-895. PMID: 30892111
infection is the most common cause of antimicrobial-associated diarrhea. Our aim was to introduce a novel and efficient clinical sickness score (CSS), and to define a detailed histologic injury score...
2.
Olson J, Navarro J, Allen J, McCulloh C, Mashburn-Warren L, Wang Y, et al.
Am J Physiol Gastrointest Liver Physiol . 2018 Jun; 315(3):G408-G419. PMID: 29848024
One significant drawback of current probiotic therapy for the prevention of necrotizing enterocolitis (NEC) is the need for at least daily administration because of poor probiotic persistence after enteral administration,...
3.
McCulloh C, Olson J, Wang Y, Zhou Y, Tengberg N, Deshpande S, et al.
J Pediatr Surg . 2018 Apr; 53(6):1215-1220. PMID: 29661576
Purpose: Necrotizing enterocolitis (NEC) remains a devastating disease in premature infants. We previously showed that four stem cell (SC) types equivalently improve experimental NEC. Exosomes are intercellular nanovesicles containing RNA,...
4.
Olson J, Deming L, King D, Rager T, Gartner S, Huibregtse N, et al.
J Pediatr Surg . 2017 Nov; PMID: 29106920
Background: Single visit surgery (SVS) consists of same-day pre-operative assessment and operation with telephone post-operative follow-up. This reduces family time commitment to 1 hospital trip rather than 2-3. We began...
5.
McCulloh C, Olson J, Wang Y, Vu J, Gartner S, Besner G
J Surg Res . 2017 Jun; 214:278-285. PMID: 28624056
Background: Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in premature infants. Increased intestinal permeability is central to NEC development. We have shown that stem cells (SCs)...
6.
McCulloh C, Olson J, Zhou Y, Wang Y, Besner G
J Pediatr Surg . 2017 Apr; 52(6):999-1005. PMID: 28366560
Purpose: Necrotizing enterocolitis (NEC) is a leading cause of gastrointestinal morbidity and mortality in premature infants. While studies have shown potential for stem cell (SC) therapy in experimental NEC, no...
7.
Olson J, Rager T, Navarro J, Mashburn-Warren L, Goodman S, Besner G
J Pediatr Surg . 2016 Apr; 51(6):936-41. PMID: 27032609
Background/purpose: Probiotics reduce the incidence of necrotizing enterocolitis (NEC) albeit only when administered at high frequency (at least daily). We have developed a novel probiotic delivery system in which probiotics...
8.
Rager T, Olson J, Zhou Y, Wang Y, Besner G
J Pediatr Surg . 2016 Mar; 51(6):942-7. PMID: 27015901
Purpose: Treatment options for necrotizing enterocolitis (NEC) remain inadequate. Bone marrow-derived mesenchymal stem cells (BM-MSCs) can protect the intestines from NEC. Exosomes are nanoparticle-sized vesicles with important cell signaling capabilities....
9.
Zhang H, Radulescu A, Chen C, Olson J, Darbyshire A, Besner G
Surgery . 2010 Oct; 149(2):276-83. PMID: 20965535
Background: The aim of the current study was to determine whether overexpression of heparin-binding epidermal growth factor-like growth factor (HB-EGF) could protect the intestines from injury after hemorrhagic shock and...
10.
Radulescu A, Zhang H, Yu X, Olson J, Darbyshire A, Chen Y, et al.
J Pediatr Surg . 2010 Oct; 45(10):1933-9. PMID: 20920709
Background: Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency and the leading surgical cause of death in premature infants. We have shown that administration of exogenous heparin-binding epidermal growth...