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Jacob J Baker

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Articles 12
Citations 347
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Recent Articles
1.
Williams J, Baker J, Zheng H, Dechow S, Fallon J, Murto M, et al.
mSphere . 2023 Sep; 8(5):e0035823. PMID: 37681985
Mycobacteria can colonize environments where the availability of metal ions is limited. Biological or inorganic chelators play an important role in limiting metal availability, and we developed a model to...
2.
Baker J, Nahar R, Petroelje B, Goswami N, Lardizabal A
J Clin Tuberc Other Mycobact Dis . 2023 May; 32:100376. PMID: 37252368
Latent tuberculosis infection (LTBI) constitutes an important public health problem because of risk of progression to TB disease. Effective treatment of multi-drug resistant (MDR) LTBI would prevent progression to MDR...
3.
Dechow S, Baker J, Murto M, Abramovitch R
J Bacteriol . 2022 Oct; 204(11):e0021222. PMID: 36226966
In defined media supplemented with single carbon sources, Mycobacterium tuberculosis (Mtb) exhibits carbon source specific growth restriction. When supplied with glycerol as the sole carbon source at pH 5.7, Mtb...
4.
Lukasiewicz K, Baker J, Zuo Y, Lu J
Front Mol Neurosci . 2021 Oct; 14:748359. PMID: 34712118
Psychedelics, compounds that can induce dramatic changes in conscious experience, have been used by humans for centuries. Recent studies have shown that certain psychedelics can induce neural plasticity by promoting...
5.
VanLangen K, Dumkow L, Axford K, Havlichek D, Baker J, Drobish I, et al.
Infect Control Hosp Epidemiol . 2019 Sep; 40(11):1236-1241. PMID: 31475658
Objective: Medical residents are an important group for antimicrobial stewardship programs (ASPs) to target with interventions aimed at improving antibiotic prescribing. In this study, we compared antimicrobial prescribing practices of...
6.
Baker J, Dechow S, Abramovitch R
Trends Microbiol . 2019 Jul; 27(11):942-953. PMID: 31324436
Mycobacterium tuberculosis (Mtb) senses and adapts to acidic host environments during the course of pathogenesis. Mutants defective in acidic pH-dependent adaptations are often attenuated during macrophage or animal infections, supporting...
7.
Baker J, Abramovitch R
Sci Rep . 2018 Mar; 8(1):4168. PMID: 29520087
Mycobacterium tuberculosis (Mtb) senses and adapts to acidic environments during the course of infection. Acidic pH-dependent adaptations include the induction of metabolic genes associated with anaplerosis and growth arrest on...
8.
Baker J, Johnson B, Abramovitch R
Mol Microbiol . 2014 Jul; 94(1):56-69. PMID: 24975990
During pathogenesis, Mycobacterium tuberculosis (Mtb) colonizes environments, such as the macrophage or necrotic granuloma, that are acidic and rich in cholesterol and fatty acids. The goal of this study was...
9.
Shen A, Baker J, Scott G, Davis Y, Ho Y, Siliciano R
J Virol . 2013 Jul; 87(17):9768-79. PMID: 23824795
Highly active antiretroviral therapy (HAART) is able to suppress human immunodeficiency virus type 1 (HIV-1) to undetectable levels in the majority of patients, but eradication has not been achieved because...
10.
Zhou T, Dang Y, Baker J, Zhou J, Zheng Y
Retrovirology . 2012 Nov; 9:93. PMID: 23134572
Background: Vpr is exclusively expressed in primate lentiviruses and contributes to viral replication and disease progression in vivo. HIV-1 Vpr has two major activities in vitro: arrest of cell cycle...