Jacob A Donoghue
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Explore the profile of Jacob A Donoghue including associated specialties, affiliations and a list of published articles.
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12
Citations
641
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Recent Articles
1.
Xiong Y, Donoghue J, Lundqvist M, Mahnke M, Major A, Brown E, et al.
Proc Natl Acad Sci U S A
. 2024 Oct;
121(42):e2315160121.
PMID: 39374396
Predictive coding is a fundamental function of the cortex. The predictive routing model proposes a neurophysiological implementation for predictive coding. Predictions are fed back from the deep-layer cortex via alpha/beta...
2.
Eisen A, Kozachkov L, Bastos A, Donoghue J, Mahnke M, Brincat S, et al.
Neuron
. 2024 Jul;
112(16):2799-2813.e9.
PMID: 39013467
Every day, hundreds of thousands of people undergo general anesthesia. One hypothesis is that anesthesia disrupts dynamic stability-the ability of the brain to balance excitability with the need to be...
3.
Tauber J, Brincat S, Stephen E, Donoghue J, Kozachkov L, Brown E, et al.
J Cogn Neurosci
. 2023 Oct;
36(2):394-413.
PMID: 37902596
A critical component of anesthesia is the loss of sensory perception. Propofol is the most widely used drug for general anesthesia, but the neural mechanisms of how and when it...
4.
Xiong Y, Donoghue J, Lundqvist M, Mahnke M, Major A, Brown E, et al.
bioRxiv
. 2023 Sep;
PMID: 37732234
Significance Statement: Neurophysiology studies have found alpha/beta oscillations (8-30Hz), gamma oscillations (40-100Hz), and spiking activity during cognition. Alpha/beta power has an inverse relationship with gamma power/spiking. This inverse relationship suggests...
5.
Bhattacharya S, Donoghue J, Mahnke M, Brincat S, Brown E, Miller E
J Cogn Neurosci
. 2022 Apr;
34(7):1274-1286.
PMID: 35468201
Oscillatory dynamics in cortex seem to organize into traveling waves that serve a variety of functions. Recent studies show that propofol, a widely used anesthetic, dramatically alters cortical oscillations by...
6.
Bastos A, Donoghue J, Brincat S, Mahnke M, Yanar J, Correa J, et al.
Elife
. 2021 Apr;
10.
PMID: 33904411
The specific circuit mechanisms through which anesthetics induce unconsciousness have not been completely characterized. We recorded neural activity from the frontal, parietal, and temporal cortices and thalamus while maintaining unconsciousness...
7.
Brincat S, Donoghue J, Mahnke M, Kornblith S, Lundqvist M, Miller E
Neuron
. 2021 Feb;
109(6):1055-1066.e4.
PMID: 33561399
Visual working memory (WM) storage is largely independent between the left and right visual hemifields/cerebral hemispheres, yet somehow WM feels seamless. We studied how WM is integrated across hemifields by...
8.
Wutz A, Loonis R, Roy J, Donoghue J, Miller E
Neuron
. 2018 Feb;
97(3):716-726.e8.
PMID: 29395915
Categories can be grouped by shared sensory attributes (i.e., cats) or a more abstract rule (i.e., animals). We explored the neural basis of abstraction by recording from multi-electrode arrays in...
9.
Zubieta-OFarrill G, Castillo-Calcaneo J, Gonzalez-Sanchez C, Villanueva-Saenz E, Donoghue J
Int J Surg Case Rep
. 2013 Mar;
4(4):359-61.
PMID: 23466683
Introduction: One-third of the world's population is infected with tuberculosis (TB), with intestinal TB representing the sixth most common presentation of extrapulmonary TB. The diagnosis of intestinal TB is a...
10.
Lewis L, Weiner V, Mukamel E, Donoghue J, Eskandar E, Madsen J, et al.
Proc Natl Acad Sci U S A
. 2012 Nov;
109(49):E3377-86.
PMID: 23129622
The neurophysiological mechanisms by which anesthetic drugs cause loss of consciousness are poorly understood. Anesthetic actions at the molecular, cellular, and systems levels have been studied in detail at steady...