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Jack M Guralnik

Explore the profile of Jack M Guralnik including associated specialties, affiliations and a list of published articles. Areas
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Articles 507
Citations 30242
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Recent Articles
1.
Whipple M, Xu S, Zhang D, Guralnik J, Guralnik J, Spring B, et al.
Am J Cardiol . 2025 Feb; PMID: 40020770
In patients with peripheral artery disease (PAD), we evaluated the effects of 12 months of walking exercise at a pace inducing ischemic leg symptoms (high intensity) on the attainment of...
2.
McDermott M, Sufit R, Domanchuk K, Volpe N, Kosmac K, Peterson C, et al.
J Vasc Surg . 2025 Jan; PMID: 39778757
Background: VM202 is a plasmid encoding two isoforms of hepatocyte growth factor. In preclinical studies, hepatocyte growth factor stimulated angiogenesis and muscle regeneration. This preliminary clinical trial tested the hypothesis...
3.
McDermott M, Dayanidhi S, Leeuwenburgh C, Wohlgemuth S, Ferrucci L, Peterson C, et al.
Vasc Med . 2024 Sep; 29(6):640-652. PMID: 39239859
Background: Mitochondrial abnormalities exist in lower-extremity peripheral artery disease (PAD), yet the association of the ankle-brachial index (ABI) with mitochondrial respiration in gastrocnemius muscle is unknown. The association of gastrocnemius...
4.
McDermott M, Martens C, Domanchuk K, Zhang D, Peek C, Criqui M, et al.
Nat Commun . 2024 Aug; 15(1):6890. PMID: 39134546
No abstract available.
5.
McDermott M, Martens C, Domanchuk K, Zhang D, Peek C, Criqui M, et al.
Nat Commun . 2024 Jun; 15(1):5046. PMID: 38871717
People with lower extremity peripheral artery disease (PAD) have increased oxidative stress, impaired mitochondrial activity, and poor walking performance. NAD+ reduces oxidative stress and is an essential cofactor for mitochondrial...
6.
Twardzik E, Guralnik J, Falvey J
Phys Ther . 2023 Dec; 104(10). PMID: 38157292
No abstract available.
7.
McDermott M, Tian L, Zhang D, Zhao L, Greenland P, Kibbe M, et al.
J Vasc Surg . 2023 Dec; 79(4):893-903. PMID: 38122859
Objective: Among people with peripheral artery disease (PAD), perceived change in walking difficulty over time, compared with people without PAD, is unclear. Among people reporting no change in walking difficulty...
8.
Huang Y, Orwig D, Hayssen H, Lu W, Gruber-Baldini A, Chiles Shaffer N, et al.
J Am Geriatr Soc . 2023 Sep; 72(1):170-180. PMID: 37725439
Background: Frailty is an important geriatric syndrome predicting adverse health outcomes in older adults. However, the longitudinal characteristics of frailty components in post-hip fracture patients are less understood. Adopting the...
9.
Whipple M, Pfammatter A, Spring B, Rejeski W, Treat-Jacobson D, Domanchuk K, et al.
J Am Heart Assoc . 2023 Aug; 12(17):e031182. PMID: 37642035
Background Overweight and obesity are associated with adverse functional outcomes in people with peripheral artery disease (PAD). The effects of weight loss in people with overweight/obesity and PAD are unknown....
10.
Ladlow P, Western M, Greaves C, Thompson J, Withall J, de Koning J, et al.
Front Public Health . 2023 Aug; 11:1151035. PMID: 37575112
Background: The prevention of mobility-related disability amongst adults is a global healthcare priority. Cost-effective community-based strategies to improve physical function and independence in older adults with mobility limitations are needed....