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Jacek Pietrzak

Explore the profile of Jacek Pietrzak including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 78
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Recent Articles
1.
Szmajda-Krygier D, Nocon Z, Pietrzak J, Krygier A, Balcerczak E
Int J Mol Sci . 2025 Feb; 26(3). PMID: 39940703
Alterations in the methylation of genetic material can influence carcinogenesis by the downregulation or overexpression of (a disintegrin-like and metalloprotease with thrombospondin motifs) protease genes. Through their proteolytic activity, these...
2.
Swiechowski R, Pietrzak J, Wosiak A, Mik M, Balcerczak E
Int J Mol Sci . 2024 Jun; 25(11). PMID: 38891994
The PI3K/AKT pathway plays a pivotal role in cellular processes, and its dysregulation is implicated in various cancers, including colorectal cancer. The present study correlates the expression levels of critical...
3.
Pietrzak J, Swiechowski R, Wosiak A, Wcislo S, Balcerczak E
Int J Mol Sci . 2024 Feb; 25(3). PMID: 38339175
The present study examines the relationship between circular RNA (circRNA) derived from three genes of the family a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTSs): , and and the host...
4.
Pietrzak J, Wosiak A, Szmajda-Krygier D, Swiechowski R, Lochowski M, Pazik M, et al.
Biomedicines . 2023 Jul; 11(7). PMID: 37509417
In the course of lung cancer, normal cells are transformed into cancerous ones, and changes occur in the microenvironment, including the extracellular matrix (ECM), which is not only a scaffold...
5.
Wosiak A, Szmajda-Krygier D, Pietrzak J, Boncela J, Balcerczak E
Bioengineering (Basel) . 2023 May; 10(5). PMID: 37237640
Purpose: Suppressor of mothers against decapentaplegic homolog 4 (SMAD family member 4, ) is involved in the adenoma-carcinoma pathway, leading to the development of colon cancer. The encoded protein is...
6.
Drogosz-Stachowicz J, Gach-Janczak K, Mirowski M, Pietrzak J, Janecki T, Janecka A
Molecules . 2023 Apr; 28(7). PMID: 37049894
Herein, the antitumor activity of a novel synthetic analog with 5,8-quinolinedione scaffold, diethyl (2-(2-chlorophenyl)-4,9-dioxo-4,9-dihydrofuro [3,2-]quinolin-3-yl)phosphonate () was investigated on two breast cancer cell lines. This analog was selected from a...
7.
Szmajda-Krygier D, Krygier A, Zebrowska-Nawrocka M, Pietrzak J, Swiechowski R, Wosiak A, et al.
Cells . 2023 Feb; 12(4). PMID: 36831334
Members of the activator protein 2 (AP-2) transcription factor (TF) family are known to play a role in both physiological processes and cancer development. The family comprises five DNA-binding proteins...
8.
Krygier A, Szmajda-Krygier D, Swiechowski R, Pietrzak J, Wosiak A, Wodzinski D, et al.
Biomolecules . 2022 Dec; 12(12). PMID: 36551272
The global scope and scale of the SARS-CoV-2 pandemic led to huge amounts of important data from clinical observations and experimental analyses being collected, in particular, regarding the long-term impact...
9.
Michalska K, Balcerczak E, Jelen A, Saed L, Pietrzak J, Zebrowska-Nawrocka M
Mol Biol Rep . 2022 Dec; 50(2):1447-1458. PMID: 36478296
Background: Multiple myeloma is one of the most common hematological malignancies worldwide. Genetic alterations may lead to the progression from monoclonal gammopathy to multiple myeloma. Additionally, the genetic background of...
10.
Wodzinski D, Wosiak A, Pietrzak J, Swiechowski R, Kordek R, Balcerczak E
Sci Rep . 2022 Jul; 12(1):11488. PMID: 35798776
The aim of this study was to evaluate the expression of the TGFB1 gene encoding the TGF-β1 cytokine in 64 patients, and then to compare it with clinico-pathological features. The...