Jaba Gamrekelashvili
Overview
Explore the profile of Jaba Gamrekelashvili including associated specialties, affiliations and a list of published articles.
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32
Citations
1692
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Recent Articles
1.
Kapanadze T, Gamrekelashvili J, Sablotny S, Schroth F, Xu Y, Chen R, et al.
J Leukoc Biol
. 2023 Dec;
115(3):573-582.
PMID: 38038378
CD115, the receptor for colony stimulating factor 1, is essential for survival and differentiation of monocytes and macrophages and is therefore frequently used to define monocyte subsets and their progenitors...
2.
Kapanadze T, Gamrekelashvili J, Sablotny S, Kijas D, Haller H, Schmidt-Ott K, et al.
Front Immunol
. 2023 Sep;
14:1240327.
PMID: 37691936
Ischemia causes an inflammatory response featuring monocyte-derived macrophages (MF) involved in angiogenesis and tissue repair. Angiogenesis and ischemic macrophage differentiation are regulated by Notch signaling Notch ligand Delta-like 1 (Dll1)....
3.
Dastagir K, Gamrekelashvili J, Dastagir N, Limbourg A, Kijas D, Kapanadze T, et al.
Sci Rep
. 2023 Aug;
13(1):12542.
PMID: 37532879
Flap surgery is a common treatment for severe wounds and a major determinant of surgical outcome. Flap survival and healing depends on adaptation of the local flap vasculature. Using a...
4.
Fleig S, Kapanadze T, Bernier-Latmani J, Lill J, Wyss T, Gamrekelashvili J, et al.
Nat Commun
. 2022 Apr;
13(1):2022.
PMID: 35440634
Tertiary lymphoid structures (TLS) are lymph node-like immune cell clusters that emerge during chronic inflammation in non-lymphoid organs like the kidney, but their origin remains not well understood. Here we...
5.
Gamrekelashvili J, Haller H, Limbourg F
Bio Protoc
. 2021 Jun;
11(9):e4007.
PMID: 34124307
Myeloid plasticity is a hallmark of the innate immune response to Toll-like receptor (TLR) activation. Here, we provide a protocol for monocyte cell fate tracking by adoptive transfer in the...
6.
Gamrekelashvili J, Kapanadze T, Sablotny S, Ratiu C, Dastagir K, Lochner M, et al.
Elife
. 2020 Jul;
9.
PMID: 32723480
Conventional Ly6C monocytes have developmental plasticity for a spectrum of differentiated phagocytes. Here we show, using conditional deletion strategies in a mouse model of Toll-like receptor (TLR) 7-induced inflammation, that...
7.
Haupt F, Krishnasamy K, Napp L, Augustynik M, Limbourg A, Gamrekelashvili J, et al.
Sci Rep
. 2019 Jul;
9(1):9798.
PMID: 31278348
During angiogenesis, single endothelial cells (EC) specialize into tip cells that guide vessel sprouting towards growth factor gradients and instruct the adjacent vessel stalk. The balance between tip and stalk...
8.
Kapanadze T, Bankstahl J, Wittneben A, Koestner W, Ballmaier M, Gamrekelashvili J, et al.
Theranostics
. 2019 Jan;
9(1):152-166.
PMID: 30662559
Methods: We combined hybrid SPECT/CT or PET/CT nuclear imaging studies of perfusion, metabolism and inflammation with multicolor flow cytometry-based cell population analysis to comprehensively analyze the ischemic tissue response and...
9.
Ziegler P, Bollrath J, Pallangyo C, Matsutani T, Canli O, De Oliveira T, et al.
Cell
. 2018 Jun;
174(1):88-101.e16.
PMID: 29909986
In colorectal cancer patients, a high density of cytotoxic CD8 T cells in tumors is associated with better prognosis. Using a Stat3 loss-of-function approach in two wnt/β-catenin-dependent autochthonous models of...
10.
Getzin T, Krishnasamy K, Gamrekelashvili J, Kapanadze T, Limbourg A, Hager C, et al.
EMBO Mol Med
. 2017 Dec;
10(2):151-159.
PMID: 29229785
Regeneration of arterial endothelium after injury is critical for the maintenance of normal blood flow, cell trafficking, and vascular function. Using mouse models of carotid injury, we show that the...