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J W M Lenders

Explore the profile of J W M Lenders including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 575
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Recent Articles
1.
Roerink M, Lenders J, Schmits I, Pistorius A, Smit J, Knoop H, et al.
J Intern Med . 2016 Oct; 281(2):179-188. PMID: 27696568
Background: Postural orthostatic tachycardia syndrome (POTS) is considered a diagnostic marker for chronic fatigue syndrome (CFS). Objectives: The aims of this study were to (i) compare POTS prevalence in a...
2.
Plouin P, Amar L, Dekkers O, Fassnacht M, Gimenez-Roqueplo A, Lenders J, et al.
Eur J Endocrinol . 2016 Apr; 174(5):G1-G10. PMID: 27048283
Phaeochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumours. Standard treatment is surgical resection. Following complete resection of the primary tumour, patients with PPGL are at risk of developing new tumoural...
3.
Moors M, Williams T, Deinum J, Eisenhofer G, Reincke M, Lenders J
Horm Metab Res . 2015 Dec; 47(13):967-72. PMID: 26667800
Primary aldosteronism encompasses 2 major underlying causes: (1) aldosterone producing adenoma and (2) bilateral adrenal hyperplasia. In addition to the aldosterone excess, increased production of other compounds of the steroidogenic...
4.
Prejbisz A, Warchol-Celinska E, Lenders J, Januszewicz A
Horm Metab Res . 2015 Nov; 47(13):973-80. PMID: 26575306
After the first cases of primary aldosteronism were described and characterized by Conn, a substantial body of experimental and clinical evidence about the long-term effects of excess aldosterone on the...
5.
Williams T, Lenders J, Burrello J, Beuschlein F, Reincke M
Horm Metab Res . 2015 Nov; 47(13):953-8. PMID: 26566104
Somatic mutations have been identified in the KCNJ5 gene (encoding the potassium channel GIRK4) in aldosterone-producing adenomas (APA). Most of these mutations are located in or near the selectivity filter...
6.
Frantzen C, Kruizinga R, van Asselt S, Zonnenberg B, Lenders J, de Herder W, et al.
Pregnancy Hypertens . 2015 May; 1(3-4):297. PMID: 26009144
No abstract available.
7.
van Berkel A, Pacak K, Lenders J
Clin Endocrinol (Oxf) . 2014 May; 81(3):329-33. PMID: 24796657
Localization of phaeochromocytomas and paragangliomas (PPGLs) should involve functional imaging as anatomical imaging modalities can either fail to locate the tumour or can be suboptimal due to an anatomical abnormality...
8.
Dekkers T, ter Meer M, Lenders J, Hermus A, Schultze Kool L, Langenhuijsen J, et al.
J Clin Endocrinol Metab . 2014 Apr; 99(7):E1341-51. PMID: 24758183
Context: Somatic mutations in genes that influence cell entry of calcium have been identified in aldosterone-producing adenomas (APAs) of adrenal cortex in primary aldosteronism (PA). Many adrenal glands removed for...
9.
van Berkel A, Lenders J, Timmers H
Eur J Endocrinol . 2013 Dec; 170(3):R109-19. PMID: 24347425
Adrenal phaechromocytomas and extra-adrenal sympathetic paragangliomas (PPGLs) are rare neuroendocrine tumours, characterised by production of the catecholamines: noradrenaline, adrenaline and dopamine. Tumoural secretion of catecholamines determines their clinical presentation which...
10.
Prejbisz A, Lenders J, Eisenhofer G, Januszewicz A
Horm Metab Res . 2013 Jan; 45(2):154-8. PMID: 23322516
Two major categories of mortality are distinguished in patients with phaeochromocytoma. First, the effects of excessive circulating catecholamines may result in lethal complications if the disease is not diagnosed and/or...