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J W Firman

Explore the profile of J W Firman including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 29
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Recent Articles
1.
Barnes D, Firman J, Belfield S, Cronin M, Vinken M, Janssen M, et al.
Arch Toxicol . 2024 Jan; 98(3):929-942. PMID: 38197913
Adverse outcome pathways (AOPs) were introduced in modern toxicology to provide evidence-based representations of the events and processes involved in the progression of toxicological effects across varying levels of the...
2.
Furuhama A, Kitazawa A, Yao J, Matos Dos Santos C, Rathman J, Yang C, et al.
SAR QSAR Environ Res . 2023 Dec; 34(12):983-1001. PMID: 38047445
Quantitative structure-activity relationship (QSAR) models are powerful in silico tools for predicting the mutagenicity of unstable compounds, impurities and metabolites that are difficult to examine using the Ames test. Ideally,...
3.
Mellor C, Marchese Robinson R, Benigni R, Ebbrell D, Enoch S, Firman J, et al.
Regul Toxicol Pharmacol . 2018 Nov; 101:121-134. PMID: 30468762
Computational approaches are increasingly used to predict toxicity due, in part, to pressures to find alternatives to animal testing. Read-across is the "new paradigm" which aims to predict toxicity by...