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J W Clack

Explore the profile of J W Clack including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
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Recent Articles
1.
Clack J, Brown P, Feldmann J, Witzmann F
Biochem Biophys Res Commun . 1994 Oct; 204(1):142-9. PMID: 7945352
We have investigated sonication-, osmotic shock-, and A23187-induced calcium and horseradish peroxidase release from phosphatidylcholine liposomes. We report that sonication and osmotic shock both cause release of liposome-entrapped horseradish peroxidase...
2.
Clack J, STEIN P
J Med Chem . 1994 Jul; 37(15):2406-10. PMID: 7794418
A purine nucleotide analog, 2'-O-(4-benzoylbenzoyl)guanosine cyclic 3',5'-monophosphate (BBcGMP), was synthesized from 4-benzoylbenzoic acid and cGMP. BBcGMP was found to inhibit several types of cyclic nucleotide phosphodiesterases (PDEs) at low concentrations....
3.
Witzmann F, Jarnot B, Parker D, Clack J
Fundam Appl Toxicol . 1994 Jul; 23(1):1-8. PMID: 7958552
This investigation was conducted to determine the comparative effect of structurally diverse peroxisome proliferators (PP) on the two-dimensional protein pattern of rat liver whole homogenates. Perfluoro-n-decanoic acid (PFDA), perfluoro-n-octanoic acid...
4.
STEIN P, Clack J
Invest Ophthalmol Vis Sci . 1994 May; 35(6):2765-8. PMID: 8188470
Purpose: To determine whether a new cyclic GMP analog, 2'-O-(4-benzoyl)benzoylguanosine 3',5' cyclic monophosphate (BB-cGMP), significantly reduces intraocular pressure in either normotensive or hypertensive eyes of rabbits. Methods: Intraocular pressure of...
5.
Witzmann F, Jarnot B, Clack J
Appl Theor Electrophor . 1994 Jan; 4(2):81-8. PMID: 7880882
This investigation was conducted to determine the comparative effect of structurally diverse peroxisome proliferators (PP) on the two-dimensional protein pattern of rat liver whole homogenates. Perfluoro-n-decanoic acid (PFDA), perfluoro-n-octanoic acid...
6.
Conner L, Clack J
Decubitus . 1993 Mar; 6(2):20-3, 26-8. PMID: 8318155
Shear stress and shear strain of human tissue were calculated in vivo using measurements derived from pelvic CT scans of three subjects lying upon three depths of foam mattress overlays...
7.
Devenny J, Clack J
Biochem Biophys Res Commun . 1991 Apr; 176(1):70-8. PMID: 1850272
Numerous studies investigating the cGMP-gated cation conductance in rod disk membranes have purported to measure efflux of Ca2+ entrapped in rod disk membrane vesicles. We have utilized sonication and osmotic...
8.
Clack J, STEIN P
Proc Natl Acad Sci U S A . 1988 Dec; 85(24):9806-10. PMID: 2462253
Low concentrations of cGMP evoked reversible single-channel currents in patches excised from liposomes that contained purified bovine opsin. Two elementary conductances, of 32 and 17 pS, were observed in the...
9.
Clack J, Pepperberg D
Vision Res . 1984 Jan; 24(12):1859-64. PMID: 6534008
Responses to test flashes were recorded extracellularly from the aspartate-treated, isolated retina of the skate, before and after topical application to the retina of solutions containing GTP, ATP, or certain...
10.
Pepperberg D, Clack J
Vision Res . 1984 Jan; 24(11):1481-6. PMID: 6533982
Flash responses of the photoreceptors in the isolated, all-rod retina of the skate were recorded extracellularly during exposure of the retina to relatively weak background light of fixed intensity. Under...