J Van Sande
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Explore the profile of J Van Sande including associated specialties, affiliations and a list of published articles.
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150
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1835
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Recent Articles
1.
Johanns M, Lai Y, Hsu M, Jacobs R, Vertommen D, Van Sande J, et al.
Nat Commun
. 2016 Mar;
7:10856.
PMID: 26952277
Biguanides such as metformin have previously been shown to antagonize hepatic glucagon-stimulated cyclic AMP (cAMP) signalling independently of AMP-activated protein kinase (AMPK) via direct inhibition of adenylate cyclase by AMP....
2.
Twyffels L, Strickaert A, Virreira M, Massart C, Van Sande J, Wauquier C, et al.
Am J Physiol Cell Physiol
. 2014 Oct;
307(12):C1102-12.
PMID: 25298423
Iodide is captured by thyrocytes through the Na(+)/I(-) symporter (NIS) before being released into the follicular lumen, where it is oxidized and incorporated into thyroglobulin for the production of thyroid...
3.
Massart C, Giusti N, Beauwens R, Dumont J, Miot F, Van Sande J
FEBS Open Bio
. 2013 Dec;
4:55-9.
PMID: 24371722
NADPH oxidases (NOXes) and dual oxidases (DUOXes) generate O2 (.-) and H2O2. Diphenyleneiodonium (DPI) inhibits the activity of these enzymes and is often used as a specific inhibitor. It is...
4.
Massart C, Hoste C, Virion A, Ruf J, Dumont J, Van Sande J
Mol Cell Endocrinol
. 2011 Jun;
343(1-2):32-44.
PMID: 21683758
H2O2 generation by dual oxidase (DUOX) at the apex of thyroid cells is the limiting factor in the oxidation of iodide and the synthesis of thyroid hormones. Its characteristics have...
5.
Dumont J, De Deken X, Miot F, Corvilain V, Contempre B, Goyens R, et al.
Bull Mem Acad R Med Belg
. 2011 Apr;
165(5-6):231-4.
PMID: 21510483
The history of the study by our group of the generation, the role and the effects of H2O2 in the thyroid, is summarized. The relations with thyroid diseases are discussed:...
6.
Song Y, Massart C, Chico-Galdo V, Jin L, De Maertelaer V, Decoster C, et al.
Mol Cell Endocrinol
. 2010 Jan;
319(1-2):56-62.
PMID: 20109522
In the literature, data obtained in signal transduction from various species thyroids and cells lines are often integrated in a common model. We investigate qualitatively and systematically, using the same...
7.
Botteaux A, Hoste C, Dumont J, Van Sande J, Allaoui A
Microbes Infect
. 2009 Mar;
11(5):537-44.
PMID: 19298864
Duox proteins are members of the NADPH oxidase (Nox) family and are responsible for hydrogen peroxide (H(2)O(2)) production by various tissue types including bronchial and intestinal mucosae. The antimicrobial killing...
8.
Duprez L, Parma J, Van Sande J, Rodien P, Dumont J, Vassart G, et al.
Trends Endocrinol Metab
. 2008 Apr;
9(4):133-40.
PMID: 18406256
Mutations of the thyrotropin receptor (TSHr) can be loss of function or gain of function. Loss-of-function mutations can affect a variety of loci in the TSHr gene. Their most common...
9.
Song Y, Driessens N, Costa M, De Deken X, Detours V, Corvilain B, et al.
J Clin Endocrinol Metab
. 2007 Aug;
92(10):3764-73.
PMID: 17666482
Context: The long-lived thyroid cell generates, for the synthesis of thyroid hormones, important amounts of H2O2 that are toxic in other cell types. This review analyzes the protection mechanisms of...
10.
Chico Galdo V, Massart C, Jin L, Vanvooren V, Caillet-Fauquet P, Andry G, et al.
Mol Cell Endocrinol
. 2006 Jul;
257-258:6-14.
PMID: 16859826
Chronic treatment of rats with acrylamide induces various tumors among which thyroid tumors are the most frequent. The aim of the present study was to develop an in vitro model...