J Ustinov
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Explore the profile of J Ustinov including associated specialties, affiliations and a list of published articles.
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41
Citations
367
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Recent Articles
1.
Hakonen E, Ustinov J, Mathijs I, Palgi J, Bouwens L, Miettinen P, et al.
Diabetologia
. 2011 Apr;
54(7):1735-43.
PMID: 21509441
Aims/hypothesis: Epidermal growth factor receptor (EGFR) signalling is essential for the proper fetal development of pancreatic islets and in the postnatal formation of an adequate beta cell mass. In this...
2.
Gao R, Ustinov J, Korsgren O, Otonkoski T
Am J Transplant
. 2007 Mar;
7(4):1021-6.
PMID: 17391142
Assuming that neogenesis contributes to long-term function of islet grafts, it is important to study the effects of immunosuppressive drugs on precursor cell proliferation and differentiation. We examined the effects...
3.
In vitro neogenesis of human islets reflects the plasticity of differentiated human pancreatic cells
Gao R, Ustinov J, Korsgren O, Otonkoski T
Diabetologia
. 2005 Sep;
48(11):2296-304.
PMID: 16193291
Aims/hypothesis: The neogenesis of islets from cultured human adult pancreatic tissue has been reported. The islet progenitors have been thought to be ductal cells. Since previous experiments have been 'contaminated'...
4.
Bondestam J, Huotari M, Moren A, Ustinov J, Kaivo-Oja N, Kallio J, et al.
Cytogenet Cell Genet
. 2002 Jun;
95(3-4):157-62.
PMID: 12063393
Transforming growth factor-beta (TGF-beta) superfamily related growth factors signal by binding to transmembrane type I and type II receptor serine/threonine kinases (RSTK), which phosphorylate intracellular Smad transcription factors in response...
5.
Tyrberg B, Ustinov J, Otonkoski T, Andersson A
Diabetes
. 2001 Mar;
50(2):301-7.
PMID: 11272140
Neogenesis is crucial for the maintenance of beta-cell mass in the human pancreas and possibly for the outcome of clinical islet transplantation. To date, no studies have reported a stimulation...
6.
Miettinen P, Huotari M, Koivisto T, Ustinov J, Palgi J, Rasilainen S, et al.
Development
. 2000 May;
127(12):2617-27.
PMID: 10821760
Pancreatic acini and islets are believed to differentiate from common ductal precursors through a process requiring various growth factors. Epidermal growth factor receptor (EGF-R) is expressed throughout the developing pancreas....
7.
Roivainen M, Rasilainen S, Ylipaasto P, Nissinen R, Ustinov J, Bouwens L, et al.
J Clin Endocrinol Metab
. 2000 Jan;
85(1):432-40.
PMID: 10634421
Enteroviruses may be involved in the pathogenesis of insulin-dependent diabetes mellitus, either through direct beta-cell infection or as triggers of autoimmunity. In the present study we investigated the patterns of...
8.
Otonkoski T, Ustinov J, Rasilainen S, Kallio E, Korsgren O, Hayry P
Transplantation
. 1999 Dec;
68(11):1674-83.
PMID: 10609943
Background: Porcine fetal pancreas is a potential source of beta cells for transplantation. The immaturity of the cells is a problem. We have defined the optimal conditions for in vitro...
9.
Lefebvre V, Otonkoski T, Ustinov J, Huotari M, Pipeleers D, Bouwens L
Diabetes
. 1998 Jan;
47(1):134-7.
PMID: 9421388
It has recently been reported that human adult beta-cells proliferate during culture on an extracellular matrix prepared from rat 804G cells and in the presence of hepatocyte growth factor (HGF)....
10.
Otonkoski T, Ustinov J, Huotari M, Kallio E, Hayry P
Transplant Proc
. 1997 Jun;
29(4):2045.
PMID: 9193518
No abstract available.