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J T Loch 3rd

Explore the profile of J T Loch 3rd including associated specialties, affiliations and a list of published articles. Areas
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1.
Wu E, Griffith R, Loch 3rd J, Kover A, Murray R, Mullen G, et al.
J Med Chem . 1995 Apr; 38(9):1558-70. PMID: 7739014
The cholinergic hypothesis of Alzheimer's disease suggests that cholinergic agonists may have therapeutic potential for treating the attendant memory deficits of the disease. As part of a program aimed at...
2.
Wu E, Loch 3rd J, Toder B, Borrelli A, GAWLAK D, Radov L, et al.
J Med Chem . 1992 Sep; 35(19):3519-25. PMID: 1404232
A series of 2-alkylisoflavone derivatives 1 was prepared with the intent to study the importance of the phenyl group (at the 3-position) of the isoflavone in imparting antihypertensive activity and...
3.
Wu E, Cole T, Davidson T, Dailey M, Doring K, FEDORCHUK M, et al.
J Med Chem . 1989 Jan; 32(1):183-92. PMID: 2909730
(3-Phenyl-7-flavonoxy)propanolamines have been shown to exhibit antihypertensive activity in spontaneously hypertensive rats. Although they are structurally similar to classical beta-adrenergic blocking compounds, their activity is not due to inhibition of...