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J Stanslas

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Articles 19
Citations 198
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Recent Articles
1.
Ngozi Nwaefulu O, Rao Sagineedu S, Kaisarul Islam M, Stanslas J
Eur Rev Med Pharmacol Sci . 2022 Feb; 26(2):367-381. PMID: 35113412
Objective: Pancreatic cancer (PaCa) is a disease that is extremely difficult to treat and is associated with a high fatality rate. The majority of patients present to hospitals with metastatic...
2.
Peh D, Wan Ahmad Kammal W, Beh P, Yong A, Tan W, Lim A, et al.
J Dermatol . 2022 Jan; 49(5):545-549. PMID: 35067938
Hydroxychloroquine (HCQ) is the first-line systemic treatment for cutaneous lupus erythematosus (CLE). Whole blood HCQ concentration (WBHCQ) was found to correlate with CLE severity among Caucasians. However, studies on Asians...
3.
Lim C, M N, Sani D, Tan S, Lim C, Kirby B, et al.
Front Pharmacol . 2021 Oct; 12:726005. PMID: 34658864
Every year, there are about 13.3 million cases of acute kidney injury (AKI). Although AKI is a preventable and treatable disease, if left untreated, it has high risk of multiple...
4.
Yahaya M, Bakar A, Stanslas J, Nordin N, Zainol M, Mehat M
BMC Biotechnol . 2021 Jun; 21(1):38. PMID: 34090414
Background: Neuroinflammation has been identified to be the key player in most neurodegenerative diseases. If neuroinflammation is left to be unresolved, chronic neuroinflammation will be establish. Such situation is due...
5.
Lim J, Sagineedu S, Yong A, Sidik S, Wong W, Stanslas J
Naunyn Schmiedebergs Arch Pharmacol . 2020 Aug; 394(1):95-105. PMID: 32840650
SRS27, an andrographolide analogue, had been proven to have therapeutic properties at a dose of 3 mg/kg in both in vitro and in vivo asthma models of our previous study....
6.
Yahaya M, Zolkiffly S, Moklas M, Abdul Hamid H, Stanslas J, Zainol M, et al.
J Immunol Res . 2020 Apr; 2020:9469210. PMID: 32258178
Alzheimer's disease (AD) has been clinically characterized by a progressive degeneration of neurons which resulted in a gradual and irreversible cognitive impairment. The accumulation of A and proteins in the...
7.
Bidin M, Shah A, Stanslas J, Seong C
Clin Chim Acta . 2019 Apr; 495:239-250. PMID: 31009602
Introduction: Chronic kidney disease (CKD) is a silent disease. Most CKD patients are unaware of their condition during the early stages of the disease which poses a challenge for healthcare...
8.
Careena S, Sani D, Tan S, Lim C, Hassan S, Norhafizah M, et al.
Evid Based Complement Alternat Med . 2018 Sep; 2018:9318789. PMID: 30186358
Cognitive disability is a common feature associated with a variety of neurological conditions including Alzheimer's Disease (AD), Parkinson's Disease (PD), brain injury, and stroke. Emerging evidence has demonstrated that neuroinflammation...
9.
Lim J, Goh F, Sagineedu S, Yong A, Sidik S, Lajis N, et al.
Toxicol Appl Pharmacol . 2016 Apr; 302:10-22. PMID: 27089844
Andrographolide (AGP) and 14-deoxy-11,12-didehydroandrographolide (DDAG), two main diterpenoid constituents of Andrographis paniculata were previously shown to ameliorate asthmatic symptoms in a mouse model. However, due to inadequacies of both compounds...
10.
Sulaiman M, Zakaria Z, Abdul Rahman A, Mohamad A, Desa M, Stanslas J, et al.
Biol Res Nurs . 2009 Aug; 11(3):293-301. PMID: 19689990
The current study was performed to evaluate the antinociceptive and antiedematogenic properties of andrographolide isolated from the leaves of Andrographis paniculata using two animal models. Antinociceptive activity was evaluated using...