J Siepmann
Overview
Explore the profile of J Siepmann including associated specialties, affiliations and a list of published articles.
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Articles
124
Citations
2100
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Recent Articles
1.
Bedulho das Lages Y, Milanino N, Verin J, Willart J, Danede F, Vincent C, et al.
Int J Pharm X
. 2024 Sep;
8:100271.
PMID: 39252691
This study evaluated the potential of poly(ethylene vinyl acetate) (EVA) copolymers as matrix formers in miniaturised implants, allowing to achieve controlled drug delivery into the inner ear. Due to the...
2.
Ramos F, Willart J, Neut C, Agossa K, Siepmann J, Siepmann F
Int J Pharm
. 2024 Apr;
657:124121.
PMID: 38621617
In-situ forming poly(lactic-co-glycolic acid) (PLGA) implants offer a great potential for controlled drug delivery for a variety of applications, e.g. periodontitis treatment. The polymer is dissolved in a water-miscible solvent....
3.
Ferraro F, Sonnleitner L, Neut C, Mahieux S, Verin J, Siepmann J, et al.
Int J Pharm X
. 2024 Feb;
7:100233.
PMID: 38379554
Polysaccharides were identified, which allow for colon targeting in human Inflammatory Bowel Disease (IBD) patients, as well as in rats and dogs (which are frequently used as animals in preclinical...
4.
Lefol L, Bawuah P, Zeitler J, Verin J, Danede F, Willart J, et al.
Int J Pharm X
. 2023 Dec;
6:100220.
PMID: 38146325
This study aimed to evaluate and better understand the potential impact that a layer of surrounding hydrogel (mimicking living tissue) can have on the drug release from PLGA microparticles. Ibuprofen-loaded...
5.
Henaff C, Siepmann J, Siepmann F, Danede F, Avettand-Fenoel M, Verin J, et al.
Int J Pharm
. 2023 Sep;
645:123416.
PMID: 37716485
Amorphous riboflavin (free base) could be produced for the first time via high energy ball milling of a commercial crystalline form (Form I). Importantly, this solid state amorphization process allowed...
6.
Bassand C, Siepmann F, Benabed L, Verin J, Freitag J, Charlon S, et al.
J Control Release
. 2023 Sep;
363:1-11.
PMID: 37714435
Different types of ibuprofen-loaded, poly (D,L lactic-co-glycolic acid) (PLGA)-based implants were prepared by 3D printing (Droplet Deposition Modeling). The theoretical filling density of the mesh-shaped implants was varied from 10...
7.
Moutaharrik S, Maroni A, Neut C, Dubuquoy C, Dubuquoy L, Foppoli A, et al.
Eur J Pharm Biopharm
. 2022 Dec;
183:13-23.
PMID: 36563887
Several formulation strategies have been proposed for oral colon delivery, particularly for the therapy of inflammatory bowel disease (IBD). However, targeting the large intestine remains a challenging goal. The aim...
8.
Rongthong T, Qnouch A, Gehrke M, Danede F, Willart J, de Oliveira P, et al.
Int J Pharm X
. 2022 Dec;
4:100141.
PMID: 36465275
The aim of this study was to better understand the long term behavior of silicone-based cochlear implants loaded with dexamethasone: in vitro as well as in vivo (gerbils). This type...
9.
Bassand C, Benabed L, Charlon S, Verin J, Freitag J, Siepmann F, et al.
J Control Release
. 2022 Dec;
353:864-874.
PMID: 36464064
3D Printing offers a considerable potential for personalized medicines. This is especially true for customized biodegradable implants, matching the specific needs of each patient. Poly(lactic-co-glycolic acid) (PLGA) is frequently used...
10.
Bassand C, Benabed L, Freitag J, Verin J, Siepmann F, Siepmann J
Int J Pharm X
. 2022 Oct;
4:100131.
PMID: 36189458
The aim of this study was to better understand the potential impact of partial vs. complete renewal of the bulk fluid during drug release measurements from poly (lactic--glycolic acid) (PLGA)-based...