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J Selbig

Explore the profile of J Selbig including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 304
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Recent Articles
1.
Jargosch M, Kroger S, Gralinska E, Klotz U, Fang Z, Chen W, et al.
Genet Mol Res . 2016 Jul; 15(2). PMID: 27420972
Data integration has become a useful strategy for uncovering new insights into complex biological networks. We studied whether this approach can help to delineate the signal transducer and activator of...
2.
Mohlig M, Floter A, Spranger J, Weickert M, Schill T, Schlosser H, et al.
Diabetologia . 2006 Sep; 49(11):2572-9. PMID: 16972044
Aims/hypothesis: Polycystic ovary syndrome (PCOS) is a risk factor of type 2 diabetes. Screening for impaired glucose metabolism (IGM) with an OGTT has been recommended, but this is relatively time-consuming...
3.
Floter A, Nicolas J, Schaub T, Selbig J
Bioinformatics . 2004 Jul; 20(10):1491-4. PMID: 15231540
Motivation: Continued development of analytical techniques based on gas chromatography and mass spectrometry now facilitates the generation of larger sets of metabolite concentration data. An important step towards the understanding...
4.
Scholz M, Gatzek S, Sterling A, Fiehn O, Selbig J
Bioinformatics . 2004 Apr; 20(15):2447-54. PMID: 15087312
Motivation: Metabolite fingerprinting is a technology for providing information from spectra of total compositions of metabolites. Here, spectra acquisitions by microchip-based nanoflow-direct-infusion QTOF mass spectrometry, a simple and high throughput...
5.
Steuer R, Kurths J, Daub C, Weise J, Selbig J
Bioinformatics . 2002 Oct; 18 Suppl 2:S231-40. PMID: 12386007
Motivation: Clustering co-expressed genes usually requires the definition of 'distance' or 'similarity' between measured datasets, the most common choices being Pearson correlation or Euclidean distance. With the size of available...
6.
Wickert L, Selbig J
J Endocrinol . 2002 Jun; 173(3):429-36. PMID: 12065232
We have generated 24 DNA-binding domain structure models of alternatively spliced or mutated steroid receptor variants by homology-based modeling. Members of the steroid receptor family dispose of a DNA-binding domain...
7.
Wickert L, Selbig J, Watzka M, Stoffel-Wagner B, Schramm J, Bidlingmaier F, et al.
J Neuroendocrinol . 2000 Sep; 12(9):867-73. PMID: 10971811
In human brain tissue, cortisol action, at basal concentrations, is mediated by the mineralocorticoid receptor (MR). An in-frame insertion of 12 bp in the MR-DNA-binding domain due to alternative splice...
8.
Selbig J, Mevissen T, Lengauer T
Bioinformatics . 2000 Apr; 15(12):1039-46. PMID: 10745994
Motivation: Prediction of protein secondary structure provides information that is useful for other prediction methods like fold recognition and ab initio 3D prediction. A consensus prediction constructed from the output...
9.
Selbig J, Argos P
Proteins . 1998 May; 31(2):172-85. PMID: 9593191
The identification of correlations between sequence patterns and structural motifs is a prerequisite in the development of protein structure prediction methods. The prediction accuracy indicates whether these correlations are discerned....
10.
Selbig J
Protein Eng . 1995 Apr; 8(4):339-51. PMID: 7567919
The protein structure prediction problem is considered as a problem of fitting a sequence into a folding motif. We focus on finding an approximative structure representation providing the best preferences...