J Scott Arn
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Explore the profile of J Scott Arn including associated specialties, affiliations and a list of published articles.
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10
Citations
206
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Recent Articles
1.
Ariyoshi Y, Takeuchi K, Pomposelli T, Ekanayake-Alper D, Shimizu A, Boyd L, et al.
Xenotransplantation
. 2020 Sep;
28(1):e12642.
PMID: 32909301
Background: Recent advances in gene editing technology have enabled the production of multi-knockout (KO) and transgenic pigs in order to overcome immunologic barriers in xenotransplantation (XTx). However, the genetic manipulations...
2.
Yamada K, Tasaki M, Sekijima M, Wilkinson R, Villani V, Moran S, et al.
Transplantation
. 2014 Sep;
98(4):411-8.
PMID: 25243511
Background: Recent survivals of our pig-to-baboon kidney xenotransplants have been markedly shorter than the graft survivals we previously reported. The discovery of high levels of porcine cytomegalovirus (pCMV) in one...
3.
Duran-Struuck R, Cho P, Teague A, Fishman B, Fishman A, Hanekamp J, et al.
Vet Immunol Immunopathol
. 2010 Jan;
135(3-4):243-56.
PMID: 20079939
This manuscript reports on five cases of spontaneous myelogenous leukemia, similar to human disease, occurring within highly inbred, histocompatible sublines of Massachusetts General Hospital (MGH) MHC-defined miniature swine. In cases...
4.
Mulder A, Kardol M, Scott Arn J, Eijsink C, Franke M, Schreuder G, et al.
Mol Immunol
. 2009 Nov;
47(4):809-15.
PMID: 19931911
Crossreactivity of anti-HLA antibodies with SLA alleles may limit the use of pig xenografts in some highly sensitized patients. An understanding of the molecular basis for this crossreactivity may allow...
5.
Griesemer A, Okumi M, Shimizu A, Moran S, Ishikawa Y, Iorio J, et al.
Transplantation
. 2009 May;
87(9):1308-17.
PMID: 19424030
Background: Survival of ABO-mismatched kidneys with stable renal function despite the persistence of anti-ABO antibodies is called accommodation. The mechanism of accommodation is unclear, but may involve complement regulatory proteins...
6.
Cho P, Lo D, Wikiel K, Rowland H, Coburn R, McMorrow I, et al.
Blood
. 2007 Aug;
110(12):3996-4004.
PMID: 17702898
The lack of transplantable tumors has limited assessment of graft-versus-tumor effects following hematopoietic cell transplantation in clinically relevant large-animal models. We describe the derivation and characterization of porcine tumor cell...
7.
Mezrich J, Haller G, Scott Arn J, Houser S, Madsen J, Sachs D
Transplantation
. 2003 Mar;
75(6):904-7.
PMID: 12660524
Three herds of miniature swine, each homozygous for a different set of alleles at the major histocompatibility complex (MHC), and five intra-MHC recombinant strains, have been reported by the authors'...
8.
Mathes D, Randolph M, Solari M, Nazzal J, Nielsen G, Scott Arn J, et al.
Transplantation
. 2003 Jan;
75(1):25-31.
PMID: 12544866
Background: The antigenicity of skin is a major obstacle to expanding human composite tissue transplantation. For example, multiple rejection episodes of the skin have been noted in clinical hand transplant...
9.
Heinz M, Huang C, Emery D, Giovino M, LeGuern A, Theodore P, et al.
Exp Hematol
. 2002 Jul;
30(7):809-15.
PMID: 12135680
Objective: The aim of this study was to develop novel markers for enrichment of hematopoietic progenitors from bone marrow of swine. Materials And Methods: We previously showed that pig bone...
10.
Mathes D, Randolph M, Bourget J, Nielsen G, Ferrera V, Scott Arn J, et al.
Transplantation
. 2002 Jul;
73(12):1880-5.
PMID: 12131681
Background: An important component of a composite tissue limb allograft (CTA) is the vascularized bone marrow and bone marrow stroma, which when transplanted could create immediate marrow space and engraftment....