J S McCaskill
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Explore the profile of J S McCaskill including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
660
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Recent Articles
1.
Fuchslin R, Maeke T, McCaskill J
Eur Phys J E Soft Matter
. 2009 Aug;
29(4):431-48.
PMID: 19697070
Biophysical chemistry of mesoscale systems and quantitative modeling in systems biology now require a simulation methodology unifying chemical reaction kinetics with essential collective physics. This will enable the study of...
2.
Kirner T, Ackermann J, Ehricht R, McCaskill J
Biophys Chem
. 2006 Oct;
79(3):163-86.
PMID: 17030317
An isothermal biochemical in vitro amplification system with two trans-cooperatively coupled amplifying DNA molecules was investigated homogeneously using a hierarchy of kinetic models and as a simplified reaction-diffusion system. In...
3.
McCaskill J, Fuchslin R, Altmeyer S
Biol Chem
. 2001 Nov;
382(9):1343-63.
PMID: 11688718
A fully stochastic chemical modelling technique is derived which describes the influence of spatial separation and discrete population size on the evolutionary stability of coupled amplification in biopolymers. The model...
4.
Fuchslin R, McCaskill J
Proc Natl Acad Sci U S A
. 2001 Jul;
98(16):9185-90.
PMID: 11470896
Genetic encoding provides a generic construction scheme for biomolecular functions. This paper addresses the key problem of coevolution and exploitation of the multiple components necessary to implement a replicable genetic...
5.
Altmeyer S, McCaskill J
Phys Rev Lett
. 2001 Jun;
86(25):5819-22.
PMID: 11415366
The error threshold for quasispecies in 1, 2, 3, and infinity dimensions is investigated by stochastic simulation and analytically. The results show a monotonic decrease in the maximal sustainable error...
6.
Bedau M, McCaskill J, Packard N, Rasmussen S, Adami C, Green D, et al.
Artif Life
. 2001 May;
6(4):363-76.
PMID: 11348587
This article lists fourteen open problems in artificial life, each of which is a grand challenge requiring a major advance on a fundamental issue for its solution. Each problem is...
7.
McCaskill J
Biosystems
. 2001 Mar;
59(2):125-38.
PMID: 11267740
The programmability and the integration of biochemical processing protocols are addressed for DNA computing using photochemical and microsystem techniques. A magnetically switchable selective transfer module (STM) is presented which implements...
8.
Penchovsky R, Birch-Hirschfeld E, McCaskill J
Nucleic Acids Res
. 2000 Nov;
28(22):E98.
PMID: 11071952
A novel approach for light-dependent covalent immobilisation of synthetic DNA oligomers to amino-coated paramagnetic beads is described. A hetero-bifunctional photo-reactive cross-linking chemical, 4-nitrophenyl 3-diazopyruvate, is applied to attach 5' amino-modified...
9.
Ellinger T, Ehricht R, McCaskill J
Chem Biol
. 1998 Dec;
5(12):729-41.
PMID: 9862794
Background: One of the key issues in the investigation of evolution is how complex systems evolved from simple chemical replicators. Theoretical work proposed several models in which complex replicating systems...
10.
Ehricht R, Kirner T, Ellinger T, Foerster P, McCaskill J
Nucleic Acids Res
. 1998 Feb;
25(22):4697-9.
PMID: 9358187
Three different types of fluorescence detection methods were employed to monitor amplification of a previously established isothermal cooperatively coupled amplification system as it can serve as a tool for the...