J S Keithly
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Explore the profile of J S Keithly including associated specialties, affiliations and a list of published articles.
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24
Citations
283
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Recent Articles
1.
Kayser O, Waters W, Woods K, Upton S, Keithly J, Kiderlen A
Planta Med
. 2001 Dec;
67(8):722-5.
PMID: 11731913
The efficacy of a series of aurones, auronols and 4-methoxy-alpha-pyrones has been screened for the ability to inhibit the intracellular growth of the parasitic protist Cryptosporidium parvum using an in...
2.
Rotte C, Stejskal F, Zhu G, Keithly J, Martin W
Mol Biol Evol
. 2001 Apr;
18(5):710-20.
PMID: 11319255
Most eukaryotes perform the oxidative decarboxylation of pyruvate in mitochondria using pyruvate dehydrogenase (PDH). Eukaryotes that lack mitochondria also lack PDH, using instead the O(2)-sensitive enzyme pyruvate : ferredoxin oxidoreductase...
3.
LaGier M, Zhu G, Keithly J
Gene
. 2001 Apr;
266(1-2):25-34.
PMID: 11290416
P1-ATPases are transporters which pump heavy metals across membranes, either to provide enzymes with essential cofactors or to remove excess, toxic metal cations from the cytosol. The first protist P1-ATPase...
4.
Zhu G, LaGier M, Hirose S, Keithly J
Exp Parasitol
. 2001 Feb;
96(4):195-201.
PMID: 11162372
We report here the identification of a novel multiprotein bridging factor type 1 from the apicomplexan Cryptosporidium parvum (CpMBF1), one of the opportunistic pathogens in AIDS patients. In slime molds,...
5.
Zhu G, Keithly J, Philippe H
Int J Syst Evol Microbiol
. 2000 Aug;
50 Pt 4:1673-1681.
PMID: 10939675
The phylogenetic position of Cryptosporidium is elusive. Although previous studies based solely upon small-subunit (SSU) rRNA sequences suggested that the genus was an early emerging lineage among the Apicomplexa, bootstrap...
6.
Zhu G, Marchewka M, Woods K, Upton S, Keithly J
Mol Biochem Parasitol
. 2000 Feb;
105(2):253-60.
PMID: 10693747
We report here the molecular analysis of a Type I fatty acid synthase in the apicomplexan Cryptosporidium parvum (CpFAS1). The CpFAS1 gene encodes a multifunctional polypeptide of 8243 amino acids...
7.
Riordan C, Langreth S, Sanchez L, Kayser O, Keithly J
J Eukaryot Microbiol
. 1999 Oct;
46(5):52S-55S.
PMID: 10519246
No abstract available.
8.
Zhu G, Marchewka M, Keithly J
FEMS Microbiol Lett
. 1999 Jul;
176(2):367-72.
PMID: 10427719
Replication protein A (RPA) consisting of three subunits is a eukaryotic single-stranded DNA (ssDNA)-binding protein involved in DNA replication, repair and recombination. We report here the identification and characterization of...
9.
Klein R, Geary T, Gibson A, Favreau M, Winterrowd C, Upton S, et al.
Microbiology (Reading)
. 1999 Mar;
145 ( Pt 2):301-307.
PMID: 10075412
Polyamine synthesis in most organisms is initiated by the decarboxylation of ornithine to form putrescine via ornithine decarboxylase (ODC). Plants, some bacteria and some fungi and protozoa generate putrescine from...
10.
Fang G, Zhu G, Burger H, Keithly J, Weiser B
J Virol Methods
. 1999 Jan;
76(1-2):139-48.
PMID: 9923748
Recent developments have made it possible to reverse transcribe RNA and amplify cDNA molecules of > 10 kb in length, including the HIV-1 genome. To use long reverse transcription combined...