J Rozga
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Explore the profile of J Rozga including associated specialties, affiliations and a list of published articles.
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94
Citations
525
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Recent Articles
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Pazzi P, Morsiani E, Vilei M, Granato A, Rozga J, Demetriou A, et al.
Aliment Pharmacol Ther
. 2002 Aug;
16(8):1547-54.
PMID: 12182755
Background: Serum bile acids are increased in liver failure, but the composition of the bile acid pool in this condition has not been studied in detail. This information is of...
3.
Avital I, Inderbitzin D, Aoki T, Tyan D, Cohen A, Ferraresso C, et al.
Biochem Biophys Res Commun
. 2001 Oct;
288(1):156-64.
PMID: 11594767
Recently it was shown that a population of cells in the bone marrow-expressing hematopoietic stem cell antigens could differentiate into hepatocytes. However, explicitly committed hepatocyte progenitors, which exhibit highly differentiated...
4.
Mizuguchi T, Hui T, Palm K, Sugiyama N, Mitaka T, Demetriou A, et al.
J Cell Physiol
. 2001 Sep;
189(1):106-19.
PMID: 11573209
Liver transplantation is the only clinically effective method of treating acute liver failure. However, wider application of this therapeutic modality is restricted primarily by shortage of donor organs. In the...
5.
Khalili T, Navarro A, Ting P, Kamohara Y, Arkadopoulos N, Solomon B, et al.
Artif Organs
. 2001 Aug;
25(7):566-70.
PMID: 11493278
Intracranial hypertension leading to brainstem coning is a major cause of death in fulminant hepatic failure (FHF). We have developed a bioartificial liver (BAL) utilizing plasma perfusion through a bioreactor...
6.
Mizuguchi T, Kamohara Y, Hui T, Neuman T, Mitaka T, Demetriou A, et al.
J Surg Res
. 2001 Jul;
99(2):385-96.
PMID: 11469916
Background: Earlier we described a model of fulminant hepatic failure (FHF) in the rat where partial hepatectomy is combined with induction of right liver lobe necrosis. In FHF rats, lack...
7.
Hui T, Rozga J, Demetriou A
J Hepatobiliary Pancreat Surg
. 2001 Apr;
8(1):1-15.
PMID: 11294283
Orthotopic liver transplantation is the only definitive therapy for patients with fulminant hepatic failure (FHF). However, due to shortage of organs, a large number of patients die before a liver...
8.
Kamohara Y, Sugiyama N, Mizuguchi T, Inderbitzin D, Lilja H, Middleton Y, et al.
Biochem Biophys Res Commun
. 2000 Jun;
273(1):129-35.
PMID: 10873574
In fulminant hepatic failure, survival is not possible without recovery of sufficient hepatocyte mass. Remarkably, only a few studies exist that provide insight into the mechanisms that control proliferation of...
9.
Lilja H, Kamohara Y, Neuman T, Demetriou A, Rozga J
Mol Cell Biol Res Commun
. 1999 Nov;
1(3):188-95.
PMID: 10425225
Mechanisms that control function and repair of the injured liver remain unclear. We hypothesized that after liver injury, elevated blood TGF-beta1 levels may reflect an adaptive response to help maintain...
10.
Detry O, Arkadopoulos N, Ting P, Kahaku E, Watanabe F, Rozga J, et al.
Am Surg
. 1999 Oct;
65(10):934-8.
PMID: 10515538
Patients with acetaminophen-induced fulminant hepatic failure (FHF) who meet the King's College Hospital criteria have a high mortality risk (>90%) if they do not undergo liver transplantation. We have developed...