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J Rosenecker

Explore the profile of J Rosenecker including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 424
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Recent Articles
1.
Guan S, Rosenecker J
Gene Ther . 2017 Jan; 24(3):133-143. PMID: 28094775
Because of its safe and effective protein expression profile, in vitro transcribed messenger RNA (IVT-mRNA) represents a promising candidate in the development of novel therapeutics for genetic diseases, vaccines or...
2.
Notheis G, Tarani L, Costantino F, Jansson A, Rosenecker J, Friederici D, et al.
Mycoses . 2006 Sep; 49 Suppl 1:37-41. PMID: 16961581
Invasive fungal infections are usually associated with immunocompromised states About 40-60% of these patients are refractory to standard antifungal therapy We describe the effect of posaconazole in the treatment of...
3.
Rudolph C, Ortiz A, Schillinger U, Jauernig J, Plank C, Rosenecker J
J Gene Med . 2004 Nov; 7(1):59-66. PMID: 15538727
Background: Polyethylenimine (PEI) has been successfully used for gene delivery to the lungs of mice via aerosol application using a whole body nebulization device. In this report we optimized the...
4.
Rosenecker J, Naundorf S, Gersting S, Hauck R, Gessner A, Nicklaus P, et al.
J Gene Med . 2003 Jan; 5(1):49-60. PMID: 12516051
Background: Plasmid DNA complexed with cationic lipids (lipoplexes) or cationic polymers (polyplexes) has been used for gene transfer into the lung. Topical gene administration of lipoplexes or polyplexes into the...
5.
Rudolph C, Schillinger U, Plank C, Gessner A, Nicklaus P, Muller R, et al.
Biochim Biophys Acta . 2002 Oct; 1573(1):75-83. PMID: 12383945
Polyethylenimine (PEI) has been shown to efficiently mediate topical gene transfer to the lungs after either direct intratracheal instillation or nebulisation. Recently, the protection of polyplexes with novel copolymers of...
6.
Rudolph C, Muller R, Rosenecker J
J Gene Med . 2002 Feb; 4(1):66-74. PMID: 11828389
Background: Aerosol drug delivery currently represents the most acceptable and convenient delivery system for repeated drug application to the lungs. Although polyethyleneimine (PEI) has recently been demonstrated to mediate gene...
7.
Rosenecker J, Eichler I, Barmeier H, von der Hardt H
Pediatr Pulmonol . 2001 Oct; 32(5):351-5. PMID: 11596159
The prevalence of cystic fibrosis-related diabetes melltitus (CFRD) is increasing as patients with cystic fibrosis (CF) live longer. Because patients with CFRD are insulin-deficient, the standard medical treatment is exogenous...
8.
Rosenecker J, Hofler R, Steinkamp G, Eichler I, Smaczny C, Ballmann M, et al.
Eur J Med Res . 2001 Sep; 6(8):345-50. PMID: 11549516
In this multicenter study, the impact of CF-related diabetes mellitus (CFRD) on pulmonary function and clinical outcome has been investigated. To better characterize the relationship between insulin deficiency and clinical...
9.
Rosenecker J
Eur J Med Res . 2000 Aug; 5(8):356-9. PMID: 10958769
The course of pulmonary disease in cystic fibrosis is variable. There are controversial data on the impact of the type of mutation on the cystic fibrosis transmembrane conductance regulator (CFTR)...
10.
Rudolph C, Lausier J, Naundorf S, Muller R, Rosenecker J
J Gene Med . 2000 Aug; 2(4):269-78. PMID: 10953918
Background: Gene transfer into the airways could be of importance for the treatment of chronic lung diseases such as cystic fibrosis. In the past few years several attempts have been...