J R Wortman
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Explore the profile of J R Wortman including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
6235
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0
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Recent Articles
1.
Gopalakrishnan V, Weiner B, Ford C, Sellman B, Hammond S, Freeman D, et al.
Immunooncol Technol
. 2022 Jun;
6:9-17.
PMID: 35757236
Immunotherapies have drastically improved clinical outcomes in a wide range of malignancies. Nevertheless, patient responses remain highly variable, and reliable biomarkers that predict responses accurately are not yet fully understood....
2.
Duryea J, Gravallese E, Wortman J, Xu C, Lu B, Kay J, et al.
Scand J Rheumatol
. 2020 Aug;
50(1):11-14.
PMID: 32757870
Erosion healing in rheumatoid arthritis (RA) is difficult to demonstrate. This extension study aimed to determine whether 2 years of teriparatide (TPTD) produces erosion healing. Subjects in a previous 12 ...
3.
Payne G, Nierman W, Wortman J, Pritchard B, Brown D, Dean R, et al.
Med Mycol
. 2018 Nov;
44(Supplement_1):S9-S11.
PMID: 30408940
Aspergillus flavus is a plant and animal pathogen that also produces the potent carcinogen aflatoxin. Aspergillus oryzae is a closely related species that has been used for centuries in the...
4.
Wortman J, Fedorova N, Crabtree J, Joardar V, Maiti R, Haas B, et al.
Med Mycol
. 2018 Nov;
44(Supplement_1):S3-S7.
PMID: 30408921
The availability of the genome sequences of multiple Aspergillus spp. presents the research community with an unprecedented opportunity for discovery. The genomes of Neosartorya fischeri and Aspergillus clavatus have been...
5.
Brito I, Yilmaz S, Huang K, Xu L, Jupiter S, Jenkins A, et al.
Nature
. 2017 Mar;
544(7648):124.
PMID: 28329759
No abstract available.
6.
Brito I, Yilmaz S, Huang K, Xu L, Jupiter S, Jenkins A, et al.
Nature
. 2016 Jul;
535(7612):435-439.
PMID: 27409808
Recent work has underscored the importance of the microbiome in human health, and has largely attributed differences in phenotype to differences in the species present among individuals. However, mobile genes...
7.
Rokas A, Payne G, Fedorova N, Baker S, Machida M, Yu J, et al.
Stud Mycol
. 2008 May;
59:11-7.
PMID: 18490942
Understanding the nature of species" boundaries is a fundamental question in evolutionary biology. The availability of genomes from several species of the genus Aspergillus allows us for the first time...
8.
Venter J, Adams M, Myers E, Li P, Mural R, Sutton G, et al.
Science
. 2001 Feb;
291(5507):1304-51.
PMID: 11181995
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp DNA sequence was generated...
9.
Jin S, Martinek S, Joo W, Wortman J, Mirkovic N, Sali A, et al.
Proc Natl Acad Sci U S A
. 2000 Jun;
97(13):7301-6.
PMID: 10860994
The tumor suppressor gene p53 in mammalian cells plays a critical role in safeguarding the integrity of genome. It functions as a sequence-specific transcription factor. Upon activation by a variety...
10.
Adams M, Celniker S, Holt R, Evans C, Gocayne J, Amanatides P, et al.
Science
. 2000 Mar;
287(5461):2185-95.
PMID: 10731132
The fly Drosophila melanogaster is one of the most intensively studied organisms in biology and serves as a model system for the investigation of many developmental and cellular processes common...