J R Wickens
Overview
Explore the profile of J R Wickens including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
848
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Recent Articles
1.
Pitcher T, Wickens J, Reynolds J
Acta Neuropsychiatr
. 2016 Jul;
18(6):304.
PMID: 27397320
No abstract available.
2.
Perk C, Wickens J, Hyland B
Neuroscience
. 2015 Mar;
294:215-26.
PMID: 25758937
Local circuits within the striatum of the basal ganglia include a small number of γ-aminobutyric acid (GABA)-ergic fast-spiking interneurons (FSI). The number of these cells is reduced in disorders of...
3.
Webster R, Cossins J, Lashley D, Maxwell S, Liu W, Wickens J, et al.
Exp Neurol
. 2013 Jun;
248:286-98.
PMID: 23797154
In the slow channel congenital myasthenic syndrome mutations in genes encoding the muscle acetylcholine receptor give rise to prolonged ion channel activations. The resulting cation overload in the postsynaptic region...
4.
Pitcher T, Wickens J, Reynolds J
Neuroscience
. 2007 Feb;
146(1):135-42.
PMID: 17320302
The spontaneously hypertensive rat (SHR) and the Wistar-Kyoto (WKY) inbred rat strains display behavioral differences characterized by relative increases and decreases in levels of activity. Both strains have subsequently been...
5.
Wickens J, MacFarlane J, Booker C, McNaughton N
Behav Brain Res
. 2004 Jun;
152(2):393-401.
PMID: 15196808
The behaviour of spontaneously hypertensive rats (SHR) may model attention-deficit hyperactivity disorder. For example, SHR are hyperactive in an open field and show high terminal rates of responding on certain...
6.
Reynolds J, Hyland B, Wickens J
Nature
. 2001 Sep;
413(6851):67-70.
PMID: 11544526
Positive reinforcement helps to control the acquisition of learned behaviours. Here we report a cellular mechanism in the brain that may underlie the behavioural effects of positive reinforcement. We used...
7.
Anson J, Hyland B, Kotter R, Wickens J
Motor Control
. 2001 Aug;
4(2):221-31.
PMID: 11500576
A movement task was used to investigate the effects of precued variables on reaction time. The task involved rapid rotation of a hand-held manipulandum to target locations and required either...
8.
Kerr J, Wickens J
J Neurophysiol
. 2001 Jan;
85(1):117-24.
PMID: 11152712
Dopamine and glutamate are key neurotransmitters involved in learning and memory mechanisms of the brain. These two neurotransmitter systems converge on nerve cells in the neostriatum. Dopamine modulation of activity-dependent...
9.
Reynolds J, Wickens J
Neuroscience
. 2000 Aug;
99(2):199-203.
PMID: 10938425
The spiny projection neurons of the neostriatum are a site at which dopamine inputs from the substantia nigra converge with excitatory inputs from the cerebral cortex. These two systems interact...
10.
Arbuthnott G, Ingham C, Wickens J
J Anat
. 2000 Aug;
196 ( Pt 4):587-96.
PMID: 10923989
After the unilateral destruction of the dopamine input to the neostriatum there are enduring changes in rat behaviour. These have been ascribed to the loss of dopamine and the animals...