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J R Lillehaug

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Articles 87
Citations 750
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Recent Articles
1.
Knappskog S, Myklebust L, Busch C, Aloysius T, Varhaug J, Lonning P, et al.
Ann Oncol . 2011 Feb; 22(10):2208-15. PMID: 21325450
Background: We have previously described the essential role of the retinoid-inducible nuclear factor (RINF) during differentiation of hematopoietic cells and suggested its putative involvement in myeloid leukemia and preleukemia. Here,...
2.
Karlsen O, Lillehaug J, Jensen H
Mol Microbiol . 2008 Aug; 70(1):15-26. PMID: 18681943
Identification of surface proteins is essential to understand bacterial communication with its environment. Analysis of the surface-associated proteins of Methylococcus capsulatus (Bath) revealed a highly dynamic structure responding closely to...
3.
Lonning P, Knappskog S, Staalesen V, Chrisanthar R, Lillehaug J
Ann Oncol . 2007 Feb; 18(8):1293-306. PMID: 17317675
Expanding knowledge, together with implementation of new techniques, has fuelled the area of translational medical research aiming at improving prognostication as well as prediction in cancer therapy. At the same...
4.
Arnesen T, Gromyko D, Pendino F, Ryningen A, Varhaug J, Lillehaug J
Oncogene . 2006 Mar; 25(31):4350-60. PMID: 16518407
Protein N-epsilon-acetylation is recognized as an important modification influencing many biological processes, and protein deacetylase inhibitors leading to N-epsilon-hyperacetylation of histones are being clinically tested for their potential as anticancer...
5.
Ibrahim S, Aarsaether N, Holsve M, Kross K, Heimdal J, Aarstad J, et al.
Oral Oncol . 2002 Nov; 39(1):37-48. PMID: 12457720
Expression profile of 588 known genes relating to tumour biology, was examined between oral squamous cell carcinomas (OSCCs) and matching normal oral mucosal tissues (NOMTs) obtained from Sudanese (n=11) and...
6.
Fluge O , Haugen D, Lillehaug J, Varhaug J
World J Surg . 2001 May; 25(5):623-31. PMID: 11369990
Met protein is a tyrosine kinase receptor for hepatocyte growth factor (HGF). c-Met has morphogenic, mitogenic, and motogenic properties and is overexpressed in many solid tumors. We studied c-met mRNA...
7.
Fluge O, Haugen D, Akslen L, Marstad A, Santoro M, Fusco A, et al.
Oncogene . 2001 Apr; 20(7):885-92. PMID: 11314023
Somatic rearrangements of the ret receptor tyrosine kinase have been consistently reported in papillary thyroid carcinomas (PTC). It is unclear whether the expression of wild-type c-ret may also be implicated...
8.
Geisler S, Lonning P, Aas T, Johnsen H, Fluge O, Haugen D, et al.
Cancer Res . 2001 Apr; 61(6):2505-12. PMID: 11289122
TP53 status [mutations, immunostaining, and loss of heterozygosity (LOH)], expression of c-erbB-2, bcl-2, and histological grading were correlated to the response to doxorubicin monotherapy (14 mg/m2) administered weekly to 90...
9.
SEITE P, Ruchaud S, Hillion J, Gendron M, Bruland O, Segal-Bendirdjian E, et al.
Cell Death Differ . 2001 Jan; 7(11):1081-9. PMID: 11139282
The IPC-81 myeloid leukaemia cells undergo apoptosis rapidly after cAMP stimulation (6 h) and cell death is prevented by early over-expression of the cAMP-inducible transcription repressor ICER, that blocks cAMP-dependent...
10.
Thorsen V, Bjorndal B, Nolan G, Fukami M, Bruland O, Lillehaug J, et al.
Biochim Biophys Acta . 2000 Oct; 1487(2-3):163-76. PMID: 11018469
The C3H/10T1/2 Cl8 HAbetaC2-1 cells used in this study express a peptide with a sequence shown to bind receptor for activated C-kinase (RACK1) and inhibit cPKC-mediated cell functions. Phorbol myristoyl...