J R Grider
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Explore the profile of J R Grider including associated specialties, affiliations and a list of published articles.
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85
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1512
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Recent Articles
1.
Kendig D, Grider J
Neurogastroenterol Motil
. 2015 Jun;
27(7):899-905.
PMID: 26095115
The role of serotonin (5-hydroxytryptamine [5-HT]) in gastrointestinal motility has been studied for over 50 years. Most of the 5-HT in the body resides in the gut wall, where it...
2.
Al-Qudah M, Alkahtani R, Akbarali H, Murthy K, Grider J
Neurogastroenterol Motil
. 2015 Jun;
27(8):1162-74.
PMID: 26088546
Background: Brain-derived neurotrophic factor (BDNF) is a neurotrophin present in the intestine where it participates in survival and growth of enteric neurons, augmentation of enteric circuits, and stimulation of intestinal...
3.
Al-Qudah M, Anderson C, Mahavadi S, Bradley Z, Akbarali H, Murthy K, et al.
Am J Physiol Gastrointest Liver Physiol
. 2013 Dec;
306(4):G328-37.
PMID: 24356881
Brain-derived neurotrophic factor (BDNF) belongs to the neurotrophin family of proteins best known for its role in neuronal survival, differentiation, migration, and synaptic plasticity in central and peripheral neurons. BDNF...
4.
Grider J, Heuckeroth R, Kuemmerle J, Murthy K
Neurogastroenterol Motil
. 2010 Mar;
22(7):779-86.
PMID: 20331804
Background: Glial cell line-derived neurotrophic factor (GDNF) is present in adult gut although its role in the mature enteric nervous system is not well defined. The aim of the present...
5.
Qiao L, Gulick M, Bowers J, Kuemmerle J, Grider J
Neurogastroenterol Motil
. 2008 Apr;
20(8):928-38.
PMID: 18373519
Brain-derived neurotrophic factor (BDNF) has been postulated to participate in inflammation-induced visceral hypersensitivity by modulating the sensitivity of visceral afferents through the activation of intracellular signalling pathways such as the...
6.
Grider J, Foxx-Orenstein A
Curr Opin Gastroenterol
. 2006 Oct;
15(1):22-5.
PMID: 17023913
Peristalsis is the main postprandial propulsive activity of the gut. It is mediated by neurons of the enteric nervous system, which form an integrated circuit composed of sensory neurons, modulatory...
7.
Grider J, Piland B
Am J Physiol Gastrointest Liver Physiol
. 2006 Sep;
292(1):G429-37.
PMID: 16973914
Short-chain fatty acids (SCFAs) accelerate colonic transit. This study examined whether this action was mediated by activation of the peristaltic reflex. SCFAs (acetate, butyrate, or propionate) were applied to the...
8.
Bornstein J, Costa M, Grider J
Neurogastroenterol Motil
. 2004 Apr;
16 Suppl 1:34-8.
PMID: 15066002
The enteric nervous system regulates intestinal motility. It contains intrinsic sensory neurones, several types of interneurones and excitatory and inhibitory motor neurones. This review summarizes our knowledge of motor neurones...
9.
Grider J
Neurogastroenterol Motil
. 2003 Dec;
15(6):607-15.
PMID: 14651596
Exposure of muscle strips to interleukin (IL)-1beta stimulates substance P (SP) expression, suggesting a link between IL-1beta and the increase in SP expression during intestinal inflammation. The present study examined...
10.
Grider J
Am J Physiol Gastrointest Liver Physiol
. 2003 Apr;
284(5):G768-75.
PMID: 12684209
A two-compartment, flat-sheet preparation of rat colon was devised, which enabled exclusive measurement of longitudinal muscle activity during the ascending and descending phases of the peristaltic reflex. A previous study...