J P Hubble
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Explore the profile of J P Hubble including associated specialties, affiliations and a list of published articles.
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44
Citations
852
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Recent Articles
1.
Hubble J, Novak P
Expert Rev Neurother
. 2009 Oct;
1(1):43-51.
PMID: 19811045
Pramipexole is a dopamine agonist that was recently introduced for the treatment of both early and advanced Parkinson's disease. Pramipexole is a synthetic aminobenzothiazole compound with a high affinity to...
2.
Li Y, Hauser M, Scott W, Martin E, Booze M, Qin X, et al.
Neurology
. 2004 Jun;
62(11):2005-9.
PMID: 15184605
Background: Similarities between Alzheimer disease (AD) and Parkinson disease (PD) suggest a possible role for apolipoprotein E (APOE) in PD. Most previous studies seeking to establish such a link used...
3.
Handforth A, Ondo W, Tatter S, Mathern G, Simpson Jr R, Walker F, et al.
Neurology
. 2003 Nov;
61(10):1401-5.
PMID: 14638963
Objective: To assess the safety and efficacy of vagus nerve stimulation (VNS) for essential tremor (ET). Methods: This was a pilot open-treatment trial at three centers, with masked videotape tremor...
4.
van der Walt J, Martin E, Scott W, Zhang F, Nance M, Watts R, et al.
Neurology
. 2003 Apr;
60(7):1189-91.
PMID: 12682333
Recently, the authors demonstrated linkage in idiopathic PD to a region on chromosome 8p that contains the N-acetyltransferase genes, NAT1 and NAT2. The authors examined NAT1 and NAT2 for association...
5.
Martin E, Scott W, Nance M, Watts R, Hubble J, Koller W, et al.
JAMA
. 2001 Nov;
286(18):2245-50.
PMID: 11710889
Context: The human tau gene, which promotes assembly of neuronal microtubules, has been associated with several rare neurologic diseases that clinically include parkinsonian features. We recently observed linkage in idiopathic...
6.
Scott W, Nance M, Watts R, Hubble J, Koller W, Lyons K, et al.
JAMA
. 2001 Nov;
286(18):2239-44.
PMID: 11710888
Context: The relative contribution of genes vs environment in idiopathic Parkinson disease (PD) is controversial. Although genetic studies have identified 2 genes in which mutations cause rare single-gene variants of...
7.
DeStefano A, Golbe L, Mark M, Lazzarini A, Maher N, Saint-Hilaire M, et al.
Neurology
. 2001 Sep;
57(6):1124-6.
PMID: 11571351
A genome-wide scan for idiopathic PD in a sample of 113 PD-affected sibling pairs is reported. Suggestive evidence for linkage was found for chromosomes 1 (214 cM, lod = 1.20),...
8.
Hubble J
Eur J Neurol
. 2000 Oct;
7 Suppl 1:15-20.
PMID: 11054154
This paper reviews the preclinical study of the novel dopamine agonist pramipexole and its use in early Parkinson's disease (PD). Emphasis will be given to those properties distinguishing this drug...
9.
Reider C, Hubble J
J Clin Epidemiol
. 2000 Aug;
53(8):863-5.
PMID: 10942870
Reliability testing was conducted on a survey instrument for a genetic epidemiological study of Parkinson's disease (PD). Information on demographics, medical history, places of residence, and occupations was collected. The...
10.
Hauser R, Koller W, Hubble J, Malapira T, Busenbark K, Olanow C
Mov Disord
. 2000 Jun;
15(3):485-9.
PMID: 10830413
Putative neuroprotective agents for Parkinson's disease can be assessed in untreated patients using progression of clinical disability as an index of disease progression. To avoid the confound associated with symptomatic...