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J P Caen

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Articles 333
Citations 1644
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Recent Articles
1.
Hornebeck W, Starkey P, Gordon J, Legrand Y, Pignaud G, Robert L, et al.
Thromb Haemost . 2019 Feb; 42(1):1681-1683. PMID: 30781919
No abstract available.
2.
Mazoyer E, Caen J, Tenza D, Cramer E
Platelets . 2010 Nov; 6(2):91-8. PMID: 21043699
The effects on platelet activation of two different tetrapeptides, KRDS present on human lactotransferrin and RGDS present on adhesive proteins such as human fibrinogen α-chain, were compared by a combination...
3.
Lozano M, Escolar G, Bellucci S, Monteagudo J, Pico M, Ordinas A, et al.
Platelets . 2006 Jun; 10(2-3):141-5. PMID: 16801084
The mechanism of the transient beneficial effect of 1-deamino(8-D-arginine) vasopressin (dDAVP) infusion in the hemostasis of some BSS patients is not fully understood. We have studied the effect of dDAVP...
4.
Lecomte-Raclet L, Aidoudi S, Lebeurier I, Bal Dit Sollier C, Kishtoo G, Aubert J, et al.
Platelets . 2006 Jun; 9(2):121-7. PMID: 16793687
A computer-assisted automatic image procedure was karyocytopoiesis in culture. This analysis system was based on acetylcholinesterase staining, a specific staining for murine bone marrow megakaryocytes, and an image capturing instrument...
5.
Trumel C, Plantavid M, Levy-Toledano S, Ragab A, Caen J, Aguado E, et al.
J Thromb Haemost . 2003 Jul; 1(2):320-9. PMID: 12871507
Thrombospondin-1 (TSP1) is abundantly secreted during platelet activation and plays a role in irreversible platelet aggregation. A peptide derived from the C-terminal domain of TSP1, RFYVVMWK (RFY) can activate human...
6.
Zhang X, Yang L, Zhao Q, Caen J, He H, Jin Q, et al.
Cell Death Differ . 2002 Jul; 9(8):790-800. PMID: 12107822
Acetylcholinesterase (AChE) plays a key role in terminating neurotransmission at cholinergic synapses. AChE is also found in tissues devoid of cholinergic responses, indicating potential functions beyond neurotransmission. It has been...
7.
Hainaud P, Bonneau M, Pignaud G, Bal Dit Sollier C, Andre P, Hadjiisky P, et al.
Atherosclerosis . 2001 Feb; 154(2):301-8. PMID: 11166762
We studied the effect of SR33805, a calcium channel blocker, in vitro on the proliferation of vascular smooth muscle cells (SMC) stimulated by foetal calf serum, basic fibroblast growth factor...
8.
Lecomte-Raclet L, Rholam M, Alemany M, Lazar N, Simenel C, Delepierre M, et al.
Biochemistry . 2000 Aug; 39(31):9612-22. PMID: 10924159
Many chemokines have direct suppressive activity in vitro and in vivo on primitive hematopoietic cells. However, few chemokine-derived peptides have shown a significant activity in inhibiting hematopoiesis. Interestingly, a peptide...
9.
Maurer A, Liu Y, Caen J, Han Z
Int J Hematol . 2000 Jun; 71(3):203-10. PMID: 10846824
The use of platelet transfusion to ensure the recovery of thrombopoiesis in patients constitutes high-cost support. The identification and cloning of recombinant human thrombopoietin (TPO) and the development of efficient...
10.
Caen J, Han Z, Bellucci S, Alemany M
Haemostasis . 1999 Sep; 29(1):27-40. PMID: 10494032
After 35 years of research, a physiological regulator of platelet production has been identified and the recombinant protein is available. With the discovery of thrombopoietin (TPO), its potential use in...