J P Bolanos
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Explore the profile of J P Bolanos including associated specialties, affiliations and a list of published articles.
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Articles
55
Citations
1419
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Recent Articles
1.
Jimenez-Blasco D, Santofimia-Castano P, Gonzalez A, Almeida A, Bolanos J
Cell Death Differ
. 2015 Apr;
22(11):1877-89.
PMID: 25909891
Neurotransmission unavoidably increases mitochondrial reactive oxygen species. However, the intrinsic antioxidant defense of neurons is weak and hence the mechanism whereby these cells are physiologically protected against oxidative damage is...
2.
Nistico R, Bolanos J, De Sarro G
Mol Neurobiol
. 2012 Aug;
46(3):545-6.
PMID: 22923365
No abstract available.
3.
Rodriguez-Rodriguez P, Fernandez E, Almeida A, Bolanos J
Cell Death Differ
. 2012 Mar;
19(10):1582-9.
PMID: 22421967
6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) is a master regulator of glycolysis by its ability to synthesize fructose-2,6-bisphosphate, a potent allosteric activator of 6-phosphofructo-1-kinase. Being a substrate of the E3 ubiquitin ligase anaphase-promoting complex-Cdh1...
4.
Cuende J, Moreno S, Bolanos J, Almeida A
Oncogene
. 2008 Jan;
27(23):3339-44.
PMID: 18212744
In neuroblastoma cells, retinoic acid induces cell cycle arrest and differentiation through degradation of the F-box protein, Skp2, and stabilization of cyclin-dependent kinase inhibitor, p27. However, the mechanism responsible for...
5.
Bolanos J, Herrero-Mendez A, Fernandez-Fernandez S, Almeida A
Biochem Soc Trans
. 2007 Oct;
35(Pt 5):1224-7.
PMID: 17956318
NO (nitric oxide) participates in a considerable number of physiological functions. At the biochemical level, most of its actions can be ascribed to its ability to bind, and activate, soluble...
6.
Diaz-Hernandez J, Moncada S, Bolanos J, Almeida A
Cell Death Differ
. 2007 Mar;
14(6):1211-21.
PMID: 17347665
In neurons, DNA is prone to free radical damage, although repair mechanisms preserve the genomic integrity. However, activation of the DNA repair system, poly(ADP-ribose) polymerase (PARP-1), is thought to cause...
7.
Gegg M, Beltran B, Salas-Pino S, Bolanos J, Clark J, Moncada S, et al.
J Neurochem
. 2003 Jun;
86(1):228-37.
PMID: 12807442
Primary culture rat astrocytes exposed to the long acting nitric oxide donor (Z)-1-[2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate (DETA-NO) for 24 h approximately double their concentration of glutathione (GSH) and show no sign of cell...
8.
Almeida A, Almeida J, Bolanos J, Moncada S
Proc Natl Acad Sci U S A
. 2001 Dec;
98(26):15294-9.
PMID: 11742096
It was recently proposed that in Jurkat cells, after inhibition of respiration by NO, glycolytically generated ATP plays a critical role in preventing the collapse of mitochondrial membrane potential (Deltapsi(m))...
9.
Cidad P, Almeida A, Bolanos J
J Neurochem
. 2001 Oct;
79(1):17-24.
PMID: 11595753
The induction of nitric oxide (NO) synthase in astrocytes by endotoxin and/or cytokine treatment is associated with increased glucose consumption and glycolysis, but the mechanism whereby this phenomenon occurs remains...
10.
Bolanos J, Vega-Agapito V, Cidad P, Almeida A
Prog Brain Res
. 2001 Sep;
132:441-54.
PMID: 11545010
No abstract available.