J Osaki
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Explore the profile of J Osaki including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
78
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Recent Articles
1.
Nakamura Y, HANEDA T, Osaki J, Miyata S, Kikuchi K
Eur J Pharmacol
. 2000 Mar;
391(1-2):39-48.
PMID: 10720633
Primary cultures of neonatal cardiac myocytes were used to determine both the identity of second messengers that are involved in vasopressin receptor-mediated effects on cardiac hypertrophy and the type of...
2.
Oi S, HANEDA T, Osaki J, Kashiwagi Y, Nakamura Y, Kawabe J, et al.
Eur J Pharmacol
. 1999 Aug;
376(1-2):139-48.
PMID: 10440099
Angiotensin II activates p21ras, and mediates cardiac hypertrophic growth through the type 1 angiotensin II receptor in cardiac myocytes. An inhibitor of 3-hydroxy-3-methyglutaryl-coenzyme A (HMG-CoA) reductase has been shown to...
3.
Osaki J, HANEDA T, Kashiwagi Y, Oi S, Fukuzawa J, Sakai H, et al.
J Hypertens
. 1998 Oct;
16(8):1193-200.
PMID: 9794724
Background: Production of heat shock protein 70 (HSP70) in the heart is induced by hemodynamic stress, but its intracellular signal transduction system has not been elucidated well. Objective: To investigate...
4.
Kashiwagi Y, HANEDA T, Osaki J, Miyata S, Kikuchi K
Hypertens Res
. 1998 Jul;
21(2):109-19.
PMID: 9661807
It is not certain whether activation of the Ras/mitogen-activated protein (MAP) kinase pathway is involved in cardiac hypertrophy. 3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, such as lovastatin, prevent farnesylation of the...
5.
Osaki J, HANEDA T, Sakai H, Kikuchi K
Cardiovasc Res
. 1997 Mar;
33(3):631-40.
PMID: 9093533
Objectives: The aim was to determine whether proto-oncogene c-fos expression and acceleration of protein synthesis by acute pressure overload to the heart were coupled with a cAMP- and protein-kinase-A-dependent system...
6.
Miyata S, HANEDA T, Osaki J, Kikuchi K
Eur J Pharmacol
. 1996 Jun;
307(1):81-8.
PMID: 8831108
Although it is well known that mechanical load to cardiac muscles causes cardiac hypertrophy, little is known about how mechanical load is transduced into the activation of intracellular signals which...
7.
HANEDA T, Okamoto K, HIROSHIMA T, Kashiwagi Y, Miyata S, Ohi S, et al.
Hypertens Res
. 1995 Jun;
18 Suppl 1:S215-9.
PMID: 8529067
The present experiments were undertaken to clarify the difference of renal dopamine production from beta 1-selective beta-blocker with and without intrinsic sympathomimetic activity (ISA). Either beta-blocker with ISA, celiprolol (100...
8.
Fukuzawa J, Osaki J, HANEDA T
Clin Exp Hypertens
. 1994 Nov;
16(6):835-52.
PMID: 7858563
The purpose of the present study were to determine the contribution of Na+/H+ exchange to pressure overload-induced cardiac hypertrophy and to examine its potential interaction with cAMP-dependent signaling pathway. Isolated...
9.
Osaki J, Hirasawa K, Tateda K, Shibata J, Miyamoto N, Shishido T, et al.
Jpn Circ J
. 1992 Sep;
56(9):955-9.
PMID: 1404849
We encountered a patient with spontaneous coronary artery dissection complicated by acute inferior myocardial infarction. A 58-year-old male was admitted to our hospital due to acute inferior myocardial infarction in...
10.
Osaki J, Nakano H, Matsumoto H, Yamazaki Y, Sakai H, Tsuji T, et al.
Nihon Kyobu Shikkan Gakkai Zasshi
. 1992 Jun;
30(6):1152-7.
PMID: 1507691
We encountered a rare case of hypersensitivity pneumonitis associated with bilateral hilar lymphadenopathy (BHL). The patient was a 53-year-old male, who developed dry cough and shortness of breath when using...