J O Dostrovsky
Overview
Explore the profile of J O Dostrovsky including associated specialties, affiliations and a list of published articles.
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Articles
146
Citations
3760
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Recent Articles
1.
Prescott I, Liu L, Dostrovsky J, Hodaie M, Lozano A, Hutchison W
Neurobiol Dis
. 2014 Aug;
71:24-33.
PMID: 25116960
Parkinson's disease (PD), characterized by the loss of dopaminergic nigrostriatal projections, is a debilitating neurodegenerative disease which produces bradykinesia, rigidity, tremor and postural instability. The dopamine precursor levodopa (L-Dopa) is...
2.
Hunter J, Dranga R, van Wyk M, Dostrovsky J
Eur J Pain
. 2014 Jul;
19(2):202-15.
PMID: 24976503
Background: The application to the skin of spatially interlaced innocuous warm (40 °C) and cool (20 °C) thermodes (termed a thermal grill--TG) can produce an unusual thermal percept, but the...
3.
Wang H, Xie Y, Chiang C, Dostrovsky J, Sessle B
Neuroscience
. 2013 Jan;
236:244-52.
PMID: 23333675
Our previous studies have demonstrated that application of the inflammatory irritant mustard oil (MO) to the tooth pulp produces trigeminal central sensitization that includes increases in mechanoreceptive field size and...
4.
Prescott I, Dostrovsky J, Moro E, Hodaie M, Lozano A, Hutchison W
Neurobiol Dis
. 2012 Dec;
51:214-21.
PMID: 23201208
Decreased inhibition and aberrant plasticity are key features in the pathophysiology of dystonia. Impaired short interval cortical inhibition and resultant increased excitability have been described for various forms of dystonia...
5.
Chiang C, Sessle B, Dostrovsky J
Neurochem Res
. 2012 May;
37(11):2419-31.
PMID: 22638776
Over the last decade, a series of studies has demonstrated that glia in the central nervous system play roles in many aspects of neuronal functioning including pain processing. Peripheral tissue...
6.
Narita N, Kumar N, Cherkas P, Chiang C, Dostrovsky J, Coderre T, et al.
Neuroscience
. 2012 May;
218:359-66.
PMID: 22609939
Our previous studies have demonstrated that application of inflammatory irritant mustard oil (MO) to the tooth pulp induces medullary glutamate release and central sensitization in the rat medullary dorsal horn...
7.
Itoh K, Chiang C, Li Z, Lee J, Dostrovsky J, Sessle B
Neuroscience
. 2011 Jul;
192:721-31.
PMID: 21763757
Central sensitization is a crucial process underlying the increased neuronal excitability of nociceptive pathways following peripheral tissue injury and inflammation. Our previous findings have suggested that extracellular adenosine 5'-triphosphate (ATP)...
8.
Wichmann T, Dostrovsky J
Neuroscience
. 2011 Jul;
198:232-44.
PMID: 21723919
Our understanding of the pathophysiology of movement disorders and associated changes in basal ganglia activities has significantly changed during the last few decades. This process began with the development of...
9.
Tsuboi Y, Iwata K, Dostrovsky J, Chiang C, Sessle B, Hu J
Eur J Neurosci
. 2011 Jun;
34(2):292-302.
PMID: 21707791
Previous studies indicate that the astroglial glutamate-glutamine shuttle may be involved in acute pulpal inflammatory pain by influencing central sensitization induced in nociceptive neurons in the trigeminal subnucleus caudalis [the...
10.
Lafreniere-Roula M, Darbin O, Hutchison W, Wichmann T, Lozano A, Dostrovsky J
Exp Neurol
. 2010 Jul;
225(2):455-8.
PMID: 20659454
Dopamine depletion in Parkinson's disease (PD) alters the neuronal activity in basal ganglia circuits. Characterizing these changes in network activity is an important step in understanding the disease and how...