J N Burroughs
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Explore the profile of J N Burroughs including associated specialties, affiliations and a list of published articles.
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38
Citations
897
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Recent Articles
1.
Crafford J, Guthrie A, van Vuuren M, Mertens P, Burroughs J, Howell P, et al.
J Virol Methods
. 2011 Apr;
174(1-2):60-4.
PMID: 21458496
A polyclonal antibody-based, group-specific, competitive ELISA (C-ELISA) for the detection of antibodies to equine encephalosis virus (EEV) was developed. The assay measures the competition between a specific guinea pig antiserum...
2.
Crafford J, Guthrie A, van Vuuren M, Mertens P, Burroughs J, Howell P, et al.
J Virol Methods
. 2003 Sep;
112(1-2):129-35.
PMID: 12951221
A polyclonal antibody-based, group-specific, indirect, sandwich ELISA (S-ELISA) for the detection of equine encephalosis virus (EEV) antigen was developed. Purified EEV particles were titrated in the S-ELISA and the limit...
3.
Takamatsu H, Mellor P, Mertens P, Kirkham P, Burroughs J, Parkhouse R
J Gen Virol
. 2003 Jan;
84(Pt 1):227-235.
PMID: 12533719
Bluetongue virus (BTV) and several other Orbivirus species are transmitted between mammalian hosts via bites from adults of certain species of Culicoides midges. However, BTV can survive for 9-12 months...
4.
Diprose J, Grimes J, Sutton G, Burroughs J, Meyer A, Maan S, et al.
J Virol
. 2002 Aug;
76(18):9533-6.
PMID: 12186935
Double-stranded RNA (dsRNA) viruses conceal their genome from the host to avoid triggering unfavorable cellular responses. The crystal structure of the core of one such virus, bluetongue virus, reveals an...
5.
Diprose J, Burroughs J, Sutton G, Goldsmith A, Gouet P, Malby R, et al.
EMBO J
. 2001 Dec;
20(24):7229-39.
PMID: 11742999
The bluetongue virus core is a molecular machine that simultaneously and repeatedly transcribes mRNA from 10 segments of viral double-stranded RNA, packaged in a liquid crystalline array. To determine how...
6.
Gouet P, Diprose J, Grimes J, Malby R, Burroughs J, Zientara S, et al.
Cell
. 1999 May;
97(4):481-90.
PMID: 10338212
The concentration of double-stranded RNA within the bluetongue virus core renders the genome segments liquid crystalline. Powder diffraction rings confirm this local ordering with a 30 A separation between strands....
7.
OHara R, Meyer A, Burroughs J, Pullen L, Martin L, Mertens P
Arch Virol Suppl
. 1998 Oct;
14:259-79.
PMID: 9785512
Attenuated (att) and wild type (wt) strains of the nine AHSV serotypes were evaluated for virulence in adult Balb C mice. Although most were avirulent in this system, isolates of...
8.
Stuart D, Gouet P, Grimes J, Malby R, Diprose J, Zientara S, et al.
Arch Virol Suppl
. 1998 Oct;
14:235-50.
PMID: 9785510
We are using crystallographic methods to investigate the structure of AHSV and BTV. Our initial approach was to investigate the structure of the major protein component of the viral core,...
9.
Pullen L, Hamblin C, OHara R, Burroughs J, Mertens P
Arch Virol Suppl
. 1998 Oct;
14:211-9.
PMID: 9785508
An established mouse model system was used to evaluate the effectiveness of the major outer core protein VP7 of African horse sickness virus (AHSV) serotype 9 as a subunit vaccine....
10.
Grimes J, Burroughs J, Gouet P, Diprose J, Malby R, Zientara S, et al.
Nature
. 1998 Oct;
395(6701):470-8.
PMID: 9774103
The structure of the core particle of bluetongue virus has been determined by X-ray crystallography at a resolution approaching 3.5 A. This transcriptionally active compartment, 700 A in diameter, represents...