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J Muthing

Explore the profile of J Muthing including associated specialties, affiliations and a list of published articles. Areas
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Articles 59
Citations 359
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Recent Articles
1.
Feuerbaum S, Saile N, Pohlentz G, Muthing J, Schmidt H
Int J Med Microbiol . 2018 Oct; 308(8):1113-1120. PMID: 30340996
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 strain EDL933 encodes the single chromosomal 9-O-acetylesterase NanS, and several copies of prophage-encoded 9-O-acetylesterases (NanS-p). These enzymes have recently been shown to cleave 5-N-acetyl-9-O-acetyl neuraminic...
2.
Karch H, Muthing J, Dobrindt U, Mellmann A
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz . 2013 Jan; 56(1):8-14. PMID: 23275950
Shiga toxin (Stx)-producing Escherichia coli (STEC), which cause hemolytic-uremic syndrome (HUS), are designated as HUSEC. Their exceptional genome variability driven by evolutionary diversification permits fast adaptation to changed environmental conditions....
3.
Muthing J, Duvar S, Nerger S, Buntemeyer H, Lehmann J
Cytotechnology . 2012 Feb; 18(3):193-206. PMID: 22358745
Primary bovine aortic endothelial cells were cultivated in serum supplemented medium without any additional growth factors. The anchorage dependent cells were propagated on Dormacell(®) microcarriers with covalently bound dimeric DEAE-groups...
4.
Duvar S, Muthing J, Mohr H, Lehmann J
Cytotechnology . 2012 Feb; 21(1):61-72. PMID: 22358607
Five types of dextran-based microcarriers (Dormacell(™), Pfeifer and Langen) with different concentrations of dimeric DEAE anion-exchange groups (nitrogen contents from 1.2 up to 2.9%) were tested as growth substrates for...
5.
Munzert E, Heidemann R, Buntemeyer H, Lehmann J, Muthing J
Biotechnol Bioeng . 2008 Jul; 56(4):441-8. PMID: 18642246
Chinese hamster ovary (CHO) cells producing the recombinant glycoprotein human antithrombin III (rhAT III) were batch cultivated in a 20-L bioreactor for 13 days. Neuraminidase activity in cell-free supernatant was...
6.
Markotic A, Marusic A, Tomac J, Muthing J
Clin Exp Immunol . 2002 May; 128(1):27-35. PMID: 11982587
This study presents a comparative analysis of gangliosides from lymphoid (spleen and thymus) and other (brain, liver, lungs and muscle) tissues of C57BL/6 mice lacking the gene for beta2-microglobulin (beta2M),...
7.
Kemminer S, Conradt H, Nimtz M, Sagi D, Peter-Katalinic J, Diekmann O, et al.
Biotechnol Prog . 2001 Oct; 17(5):809-21. PMID: 11587568
R24 is a mouse IgG3 monoclonal antibody (mab) that reacts with the ganglioside GD3 expressed by cells of neuroectodermal origin. The anti-tumor activity of R24 has been demonstrated in initial...
8.
Metelmann W, Peter-Katalinic J, Muthing J
J Am Soc Mass Spectrom . 2001 Aug; 12(8):964-73. PMID: 11506229
Nano-ESI QTOF MS was used for sensitive mapping and sequencing of single molecular species in complex ganglioside mixtures obtained from human granulocytes, where the fucosylated carbohydrate chains of granulocyte gangliosides...
9.
Vukelic Z, Metelmann W, Muthing J, Kos M, Peter-Katalinic J
Biol Chem . 2001 Apr; 382(2):259-74. PMID: 11308024
Gangliosides from histopathologically-defined human cerebrum-resembling remnant and cerebellum from 37 and 30 gestational week-old anencephaluses were identified using mass spectrometry and high performance thin layer chromatography combined with immunochemical analysis...
10.
Muthing J, Burg M
Carbohydr Res . 2001 Mar; 330(3):347-56. PMID: 11270813
Cytosolic Chinese hamster ovary (CHO) cell sialidase has been cloned as a soluble glutathione S-transferase (GST)-sialidase fusion protein with an apparent molecular weight of 69 kD in Escherichia coli. The...