J Michael Wells
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Explore the profile of J Michael Wells including associated specialties, affiliations and a list of published articles.
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120
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Recent Articles
1.
Barjaktarevic I, Hixson R, Zhuang Z, Buhr R, Tejwani V, Barr R, et al.
Ann Am Thorac Soc
. 2025 Mar;
PMID: 40068143
Background: Reliable data about the natural history of lung function decline in alpha-1 antitrypsin (AAT) deficient Pi*MZ heterozygotes is largely missing. We hypothesized that, in adults with a tobacco smoking...
2.
Khandelwal N, Hinson J, Nguyen T, Daviano A, Xu Y, Suehs B, et al.
J Health Econ Outcomes Res
. 2025 Feb;
12(1):66-74.
PMID: 39991078
Alpha-1 antitrypsin deficiency (AATD) testing rates and associated clinical and economic outcomes data in the US Medicare population are limited. To characterize individuals with AATD, describe clinical outcomes/healthcare research utilization...
3.
Wechsler M, Wells J
ERJ Open Res
. 2024 Sep;
10(5).
PMID: 39319045
Inflammation drives COPD pathogenesis and exacerbations. Although the conceptual framework and major players in the inflammatory milieu of COPD have been long established, the nuances of cellular interactions and the...
4.
Gastanadui M, Margaroli C, Litovsky S, Richter R, Wang D, Xing D, et al.
Arterioscler Thromb Vasc Biol
. 2024 Sep;
44(11):e264-e276.
PMID: 39234691
Background: Coronary atherosclerotic plaques susceptible to acute coronary syndrome have traditionally been characterized by their surrounding cellular architecture. However, with the advent of intravascular imaging, novel mechanisms of coronary thrombosis...
5.
Curtis J, Bateman L, Murray S, Couper D, Labaki W, Freeman C, et al.
Chronic Obstr Pulm Dis
. 2024 Aug;
11(5):444-459.
PMID: 39159077
Background: The biological mechanisms leading some tobacco-exposed individuals to develop early-stage chronic obstructive pulmonary disease (COPD) are poorly understood. This knowledge gap hampers development of disease-modifying agents for this prevalent...
6.
Ruvuna L, Hijazi K, Guzman D, Guo C, Loureiro J, Khokhlovich E, et al.
medRxiv
. 2024 Aug;
PMID: 39148837
Rationale: Identification and validation of circulating biomarkers for lung function decline in COPD remains an unmet need. Objective: Identify prognostic and dynamic plasma protein biomarkers of COPD progression. Methods: We...
7.
Myers L, Quint J, Hawkins N, Putcha N, Hamilton A, Lindenauer P, et al.
Am J Respir Crit Care Med
. 2024 Aug;
210(6):715-729.
PMID: 39133888
Individuals with chronic obstructive pulmonary disease (COPD) are often at risk for or have comorbid cardiovascular disease and are likely to die of cardiovascular-related causes. To prioritize a list of...
8.
Zhang W, Rice M, Hoffman K, Oromendia C, Barjaktarevic I, Wells J, et al.
JCI Insight
. 2024 Jun;
9(12).
PMID: 38912587
No abstract available.
9.
Chiles 3rd J, Wilson A, Tindal R, Lavin K, Windham S, Rossiter H, et al.
J Cachexia Sarcopenia Muscle
. 2024 Apr;
15(3):1016-1029.
PMID: 38649783
Background: Skeletal muscle dysfunction is a common extrapulmonary manifestation of chronic obstructive pulmonary disease (COPD). Alterations in skeletal muscle myosin heavy chain expression, with reduced type I and increased type...
10.
Idigo A, Wells J, Brown M, Wiener H, Griffin R, Cutter G, et al.
Heart Lung
. 2024 Feb;
65:31-39.
PMID: 38382142
Background: How socio-demographic characteristics and comorbidities affect bacterial community-acquired pneumonia (CAP) prognosis during/after hospitalization is important in disease management. Objectives: To identify predictors of medical intensive care unit (MICU) admission,...