J McCafferty
Overview
Explore the profile of J McCafferty including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
1515
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0
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Recent Articles
1.
Cacciottolo T, Perikari A, van der Klaauw A, Henning E, Stadler L, Keogh J, et al.
QJM
. 2019 Sep;
112(9):724-729.
PMID: 31505685
No abstract available.
2.
Mouzannar R, McCafferty J, Benedetto G, Richardson C
Int J Genomics Proteomics
. 2011 Jul;
2(1):34-49.
PMID: 21743783
Elevated reactive oxidative species (ROS) are cytotoxic, and chronic elevated levels of ROS have been implicated in multiple diseases as well as cellular transformation and tumor progression. However, the potential...
3.
Pershad K, Pavlovic J, Graslund S, Nilsson P, Colwill K, Karatt-Vellatt A, et al.
Protein Eng Des Sel
. 2010 Feb;
23(4):279-88.
PMID: 20164216
To demonstrate the utility of phage display in generating highly specific antibodies, affinity selections were conducted on 20 related Src Homology 2 (SH2) domains (ABL1, ABL2, BTK, BCAR3, CRK, FYN,...
4.
Warford A, Flack G, Conquer J, Zola H, McCafferty J
J Immunol Methods
. 2006 Dec;
318(1-2):125-37.
PMID: 17141799
Immunohistochemistry (IHC) is a powerful technique for identifying sites of protein expression in tissues at the cellular and sub-cellular level. Here we have investigated the potential of using IHC for...
5.
Rebello G, Hallam N, Smart G, Farquharson D, McCafferty J
BMJ
. 2001 Aug;
323(7304):109.
PMID: 11480413
No abstract available.
6.
Rebello G, Hallam N, Smart G, Farquharson D, McCafferty J
BMJ
. 2001 Apr;
322(7291):893-4.
PMID: 11302900
No abstract available.
7.
McCafferty J, Glover D
Curr Opin Struct Biol
. 2000 Sep;
10(4):417-20.
PMID: 10981628
Many early drug candidates derived from biotechnology failed in clinical trials because of their low affinity/specificity, short half-lives or immunogenicity. Protein engineering techniques have been applied to circumvent some of...
8.
Cochrane D, Webster C, Masih G, McCafferty J
J Mol Biol
. 2000 Mar;
297(1):89-97.
PMID: 10704309
The cytoplasmic domain of the Fc gamma receptor IIB (FcgammaRIIB) can be successfully displayed on the surface of filamentous phage, and after phosphorylation in vitro, can interact specifically with the...
9.
Nelson J, Kennedy J, Pollock B, Narayan M, Nobler M, Robin D, et al.
Am J Psychiatry
. 1999 Jul;
156(7):1024-8.
PMID: 10401446
Objective: This study compared the efficacy, tolerability, and safety of paroxetine and nortriptyline in depressed patients with ischemic heart disease. Method: After a 2-week, single-blind placebo lead-in phase, 81 outpatients...
10.
Osbourn J, Earnshaw J, Johnson K, Parmentier M, Timmermans V, McCafferty J
Nat Biotechnol
. 1998 Aug;
16(8):778-81.
PMID: 9702779
The seven trans-membrane chemokine receptor CCR-5 is a coreceptor for macrophage tropic HIV-1 strains. CCR-5 responds to a number of chemokines, including macrophage inflammatory protein (MIP)-1 alpha. We describe the...