J Mark Wilkinson
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Explore the profile of J Mark Wilkinson including associated specialties, affiliations and a list of published articles.
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97
Citations
1481
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Recent Articles
1.
Katsoula G, Lawrence J, Arruda A, Tutino M, Balogh P, Southam L, et al.
Am J Hum Genet
. 2024 Nov;
111(12):2735-2755.
PMID: 39579762
Translational efforts in osteoarthritis are hampered by a gap in our understanding of disease processes at the molecular level. Here, we present evidence of pronounced transcriptional changes in high- and...
2.
Lamb J, Evans J, Relton S, Whitehouse M, Wilkinson J, Pandit H
PLoS Med
. 2024 Oct;
21(10):e1004462.
PMID: 39352892
Background: Postoperative periprosthetic femoral fracture (POPFF) after total hip replacement (THR) requires complex surgery and is associated with a high morbidity, mortality, and cost. Although the United Kingdom based National...
3.
Kreitmaier P, Swift D, Wilkinson J, Zeggini E
Osteoarthritis Cartilage
. 2024 Jul;
32(9):1126-1133.
PMID: 39053729
Objective: Osteoarthritis is a common and complex joint disorder that shows higher prevalence and greater disease severity in women. Here, we investigate genome-wide methylation profiles of primary chondrocytes from osteoarthritis...
4.
Leta T, Lie S, Fenstad A, Lygre S, Lindberg-Larsen M, Pedersen A, et al.
JAMA Netw Open
. 2024 May;
7(5):e2412898.
PMID: 38780939
Importance: Despite increased use of antibiotic-loaded bone cement (ALBC) in joint arthroplasty over recent decades, current evidence for prophylactic use of ALBC to reduce risk of periprosthetic joint infection (PJI)...
5.
Kreitmaier P, Park Y, Swift D, Gilly A, Wilkinson J, Zeggini E
Hum Mol Genet
. 2023 Nov;
33(6):501-509.
PMID: 37975894
Osteoarthritis is a prevalent, complex disease of the joints, and affects multiple intra-articular tissues. Here, we have examined genome-wide DNA methylation profiles of primary infrapatellar fat pad and matched blood...
6.
Leta T, Fenstad A, Lygre S, Lie S, Lindberg-Larsen M, Pedersen A, et al.
Acta Orthop
. 2023 Aug;
94:416-425.
PMID: 37565339
Background And Purpose: Antibiotic-loaded bone cement (ALBC) and systemic antibiotic prophylaxis (SAP) have been used to reduce periprosthetic joint infection (PJI) rates. We investigated the use of ALBC and SAP...
7.
McLaughlin J, Kipping R, Owen-Smith A, McLeod H, Hawley S, Wilkinson J, et al.
BMC Med
. 2023 Jun;
21(1):202.
PMID: 37308999
Background: Despite their widespread use, the impact of commissioners' policies for body mass index (BMI) for access to elective surgery is not clear. Policy use varies by locality, and there...
8.
Kehayova Y, Wilkinson J, Rice S, Loughlin J
Arthritis Res Ther
. 2023 May;
25(1):83.
PMID: 37208701
Background: Investigation of cartilage and chondrocytes has revealed that the osteoarthritis risk marked by the independent DNA variants rs11583641 and rs1046934 mediate their effects by decreasing the methylation status of...
9.
Faber B, Frysz M, Hartley A, Ebsim R, Boer C, Saunders F, et al.
Arthritis Rheumatol
. 2023 Jan;
75(6):900-909.
PMID: 36662418
Objective: To examine the genetic architecture of cam morphology using alpha angle (AA) as a proxy measure and conduct an AA genome-wide association study (GWAS) followed by Mendelian randomization (MR)...
10.
Kehayova Y, Wilkinson J, Rice S, Loughlin J
Arthritis Rheumatol
. 2022 Dec;
75(6):910-922.
PMID: 36538011
Objective: Over 100 DNA variants have been associated with osteoarthritis (OA), including rs1046934, located within a linkage disequilibrium block encompassing part of COLGALT2 and TSEN15. The present study was undertaken...