J Maclean
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Explore the profile of J Maclean including associated specialties, affiliations and a list of published articles.
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Articles
64
Citations
1070
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Recent Articles
1.
Heath D, El-Hakim H, Al-Rahji Y, Eksteen E, Uwiera T, Isaac A, et al.
J Otolaryngol Head Neck Surg
. 2021 Jul;
50(1):48.
PMID: 34266488
Introduction: Diagnosis and treatment of obstructive sleep apnea (OSA) in children is often delayed due to the high prevalence and limited physician and sleep testing resources. As a result, children...
2.
Kirk R, Ratcliffe A, Noonan G, Uosis-Martin M, Lyth D, Bardell-Cox O, et al.
RSC Med Chem
. 2021 Jun;
11(12):1379-1385.
PMID: 34095845
Building on our previously-reported novel tricyclic topoisomerase inhibitors (NTTIs), we disclose the discovery of REDX07965, which has an MIC of 0.5 μg mL against , favourable pharmacokinetic properties, selectivity human...
3.
Kirk R, Ratcliffe A, Noonan G, Uosis-Martin M, Lyth D, Bardell-Cox O, et al.
RSC Med Chem
. 2021 Jun;
11(12):1366-1378.
PMID: 34095844
The alarming reduction in drug effectiveness against bacterial infections has created an urgent need for the development of new antibacterial agents that circumvent bacterial resistance mechanisms. We report here a...
4.
Wu P, Szczesniak M, Maclean J, Graham P, Quon H, Choo L, et al.
Dis Esophagus
. 2018 Nov;
32(6).
PMID: 30462194
Long-term pharyngeal dysphagia is a common complication following head and neck cancer (HNC) therapies. High-level evidence for pharyngoesophageal junction (POJ) dilatation as a treatment in this population is lacking. We...
5.
Szczesniak M, Wu P, Maclean J, Omari T, Cook I
Neurogastroenterol Motil
. 2018 May;
30(10):e13374.
PMID: 29797467
Introduction: Restrictive defects of the pharyngo-esophageal junction (PEJ) are common in both structural and neurological disorders and are amenable to therapies aiming to reduce outflow resistance. Intrabolus pressure (IBP) acquired...
6.
Maclean J, Fersht N, Sullivan K, Kayani I, Bomanji J, Dickson J, et al.
Clin Oncol (R Coll Radiol)
. 2017 Apr;
29(7):448-458.
PMID: 28433399
Aims: The increasing use of highly conformal radiation techniques to treat meningioma confers a greater need for accurate targeting. Several groups have shown that positron emission tomography/computed tomography (PET/CT) information...
7.
8.
Szczesniak M, Maclean J, Zhang T, Liu R, Cock C, Rommel N, et al.
Neurogastroenterol Motil
. 2015 Jun;
27(8):1183-9.
PMID: 26031361
Background: Pharyngeal automated impedance manometry (AIM) analysis is a novel non-radiological method to analyze swallowing function based on impedance-pressure recordings. In dysphagic head and neck cancer patients, we evaluated the...
9.
Omari T, Szczesniak M, Maclean J, Myers J, Rommel N, Cock C, et al.
Dis Esophagus
. 2014 Dec;
29(2):166-73.
PMID: 25515292
Pressure-flow analysis quantifies the interactions between bolus transport and pressure generation. We undertook a pilot study to assess the interrelationships between pressure-flow metrics and fluoroscopically determined bolus clearance and bolus...
10.
Szczesniak M, Maclean J, Zhang T, Graham P, Cook I
Clin Oncol (R Coll Radiol)
. 2014 Sep;
26(11):697-703.
PMID: 25239671
Aims: Dysphagia is a well-recognised acute complication after radiotherapy. However, knowledge about the long-term prevalence and effect remains limited. The aims of this study were to determine the prevalence, severity,...