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J M van Noort

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Articles 53
Citations 725
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Recent Articles
1.
Gorter R, Stephenson J, Nutma E, Anink J, de Jonge J, Baron W, et al.
Neuropathol Appl Neurobiol . 2018 Oct; 45(5):459-475. PMID: 30346063
Aims: Amyotrophic lateral sclerosis (ALS) is a chronic neurodegenerative disease characterized by progressive loss of motor neurons, muscle weakness, spasticity, paralysis and death usually within 2-5 years of onset. Neuroinflammation...
2.
Gorter R, Nutma E, Jahrei M, de Jonge J, Quinlan R, van der Valk P, et al.
Clin Exp Immunol . 2018 Jul; 194(2):137-152. PMID: 30014472
Multiple sclerosis (MS) is a chronic neurodegenerative disease characterized by demyelination, inflammation and neurodegeneration throughout the central nervous system. Although spinal cord pathology is an important factor contributing to disease...
3.
Gortz A, Peferoen L, Gerritsen W, van Noort J, Bugiani M, Amor S
Neuropathol Appl Neurobiol . 2017 Mar; 44(4):363-376. PMID: 28319253
Aims: X-linked adrenoleukodystrophy (X-ALD) is a genetic white matter disorder in which demyelination occurs due to accumulation of very long-chain fatty acids. Inflammation in the brain white matter is a...
4.
Verbeek R, Bsibsi M, Plomp A, van Neerven R, te Biesebeke R, van Noort J
Benef Microbes . 2011 Aug; 1(2):109-19. PMID: 21840799
The probiotic properties of commensal bacteria including lactobacilli and bifidobacteria are likely to be determined at least in part by their effects on dendritic cells. Like traditional immune stimulants such...
5.
Dijkstra S, Kooij G, Verbeek R, van der Pol S, Amor S, Geisert Jr E, et al.
Neurobiol Dis . 2008 Jul; 31(3):413-21. PMID: 18586096
Leukocyte infiltration is a key step in the development of demyelinating lesions in multiple sclerosis (MS), and molecules mediating leukocyte-endothelial interactions represent prime candidates for the development of therapeutic strategies....
6.
Zaadstra B, Chorus A, Buuren S, Kalsbeek H, van Noort J
Mult Scler . 2008 Jan; 14(3):307-13. PMID: 18208871
Previous studies have suggested an association between multiple sclerosis (MS) and infectious mononucleosis (IM) but data on the exact strength of this association or its selectivity have been conflicting. In...
7.
van Noort J
J Pathol . 2007 Dec; 214(2):267-75. PMID: 18161755
Stress proteins or heat shock proteins (HSPs) are ubiquitous cellular components that have long been known to act as molecular chaperones. By assisting proper folding and transport of proteins, and...
8.
van Noort J, Verbeek R, Meilof J, Polman C, Amor S
Mult Scler . 2006 Jun; 12(3):287-93. PMID: 16764341
Human T-cell responses to the stress protein alpha B-crystallin in multiple sclerosis (MS)-affected brain samples are dominant when compared to other myelin antigens. The establishment of the apparent autoimmune repertoire...
9.
Nelissen I, Gveric D, van Noort J, Cuzner M, Opdenakker G
Neuropathol Appl Neurobiol . 2006 Jan; 32(1):15-22. PMID: 16409549
In multiple sclerosis (MS), the matrix metalloprotease (MMP) gelatinase B/MMP-9 and platelet endothelial cell adhesion molecule (PECAM)-1 have both been implicated in trans-endothelial infiltration of leucocytes into the brain, but...
10.
Celet B, Akman-Demir G, Serdaroglu P, Yentur S, Tasci B, van Noort J, et al.
J Neurol . 2001 Feb; 247(12):935-9. PMID: 11200685
alpha B-Crystallin, a small heat shock protein, is an immunodominant antigen with increased tissue expression in demyelination. To investigate the humoral response against alpha B-crystallin, the sera and CSF samples...