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J M Sonner

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Articles 14
Citations 256
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Recent Articles
1.
Werner D, Swihart A, Rau V, Jia F, Borghese C, McCracken M, et al.
J Pharmacol Exp Ther . 2010 Sep; 336(1):134-44. PMID: 20807777
The mechanism by which the inhaled anesthetic isoflurane produces amnesia and immobility is not understood. Isoflurane modulates GABA(A) receptors (GABA(A)-Rs) in a manner that makes them plausible targets. We asked...
2.
Eger 2nd E, Fisher D, Dilger J, Sonner J, Evers A, Franks N, et al.
Anesthesiology . 2001 Jun; 94(5):915-21. PMID: 11388545
No abstract available.
3.
Dutton R, Maurer A, Sonner J, Fanselow M, Laster M, Eger 2nd E
Anesthesiology . 2001 May; 94(3):514-9. PMID: 11374614
Background: Recent reports suggest that one type of learning, fear conditioning to context, requires more neural processing than a related type, fear conditioning to tone. To determine whether these types...
4.
Joo D, Gong D, Sonner J, Jia Z, MacDonald J, Eger 2nd E, et al.
Anesthesiology . 2001 May; 94(3):478-88. PMID: 11374610
Background: The alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) subtype of glutamate receptor mediates fast excitatory neurotransmission in the central nervous system. Many general anesthetics inhibit AMPA receptors in vitro; however, it is not...
5.
Zhang Y, Wu S, Eger 2nd E, Sonner J
Anesth Analg . 2001 Jan; 92(1):123-7. PMID: 11133613
Unlabelled: Inhaled anesthetics produce immobility (a cardinal aspect of general anesthesia) by an action on the spinal cord, possibly by potentiating the responses of gamma-amino-n-butyric acid (GABA(A)) and glycine receptors...
6.
Maurer A, Sessler D, Eger 2nd E, Sonner J
Anesth Analg . 2000 Sep; 91(4):1013-6. PMID: 11004066
Inhaled and other anesthetics profoundly affect the central nervous system, causing amnesia, immobility in the face of noxious stimulation, and depression of thermoregulation. Nonimmobilizers, inhaled compounds whose lipophilicity suggests that...
7.
Sonner J, Gong D, Eger 2nd E
Anesth Analg . 2000 Aug; 91(3):720-6. PMID: 10960407
Unlabelled: We measured the naturally occurring variability in anesthetic potency, defined by the minimum alveolar anesthetic concentrations (MACs) of inhaled anesthetics required to produce immobility in response to noxious stimuli,...
8.
Zhang Y, Eger 2nd E, Dutton R, Sonner J
Anesth Analg . 2000 Jul; 91(2):462-6. PMID: 10910869
Unlabelled: We investigated the hyperalgesic (antianalgesic) effect of the inhaled anesthetics isoflurane, halothane, nitrous oxide, and diethyl ether, or the nonimmobilizer 1, 2-dichlorohexafluorocyclobutane at subanesthetic partial pressures (or, for the...
9.
Sonner J, Gong D, Li J, Eger 2nd E, Laster M
Anesth Analg . 1999 Oct; 89(4):1030-4. PMID: 10512285
Unlabelled: In this study, we measured the minimum alveolar anesthetic concentration (MAC) in several mouse strains, including strains used in the construction of genetically engineered mice. This is important because...
10.
Eger 2nd E, Halsey M, Harris R, Koblin D, Pohorille A, Sewell J, et al.
Anesth Analg . 1999 Jun; 88(6):1395-400. PMID: 10357351
Unlabelled: All series of volatile and gaseous compounds contain members that can produce anesthesia, as defined by the minimum alveolar anesthetic concentration (MAC) required to produce immobility in response to...