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J M Hershman

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Articles 328
Citations 2620
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Recent Articles
1.
Zhang L, Sharma S, Hershman J, Brent G, Dubinett S, Huang M
Cancer Gene Ther . 2005 Jul; 13(1):74-81. PMID: 16052231
While external ionizing radiation has been used for treating non-small cell lung cancer (NSCLC), improved efficacy of this modality would be an important advance. Ectopic expression of the sodium iodide...
2.
Singh N, Weisler S, Hershman J
Thyroid . 2001 Nov; 11(10):967-71. PMID: 11716045
To determine the acute effect of calcium, we measured levothyroxine absorption after ingestion of thyroxine (T4) with and without simultaneous ingestion of calcium (as calcium carbonate) in seven volunteers without...
3.
Huang M, Batra R, Kogai T, Lin Y, Hershman J, Lichtenstein A, et al.
Cancer Gene Ther . 2001 Sep; 8(8):612-8. PMID: 11571539
Radioiodide is an effective therapy for thyroid cancer. This treatment modality exploits the thyroid-specific expression of the sodium iodide symporter (NIS) gene, which allows rapid internalization of iodide into thyroid...
4.
Yip I, Go V, Hershman J, Wang H, Elashoff R, DeShields S, et al.
Pancreas . 2001 Aug; 23(2):197-203. PMID: 11484922
Introduction: The relation between insulin-leptin-visceral fat axis during weight loss has not been studied previously. Aims: To evaluate the insulin, leptin, and abdominal adiposity relation during weight loss in patients...
5.
Kogai T, Hershman J, Motomura K, Endo T, Onaya T, Brent G
Endocrinology . 2001 Jul; 142(8):3369-79. PMID: 11459780
The absence of TSH-stimulated radioiodide uptake in differentiated thyroid cancer is associated with a high recurrence rate and reduced survival. We studied regulation of the sodium/iodide symporter gene in human...
6.
Ohta K, Endo T, Haraguchi K, Hershman J, Onaya T
J Clin Endocrinol Metab . 2001 May; 86(5):2170-7. PMID: 11344222
Ligands for peroxisome proliferator-activated receptor gamma (PPARgamma) induce apoptosis and exert antiproliferative effects on several carcinoma cell lines. The present study investigates the expression of PPARgamma and the possibility that...
7.
Robins S, Collins D, Wittes J, Papademetriou V, Deedwania P, Schaefer E, et al.
JAMA . 2001 Apr; 285(12):1585-91. PMID: 11268266
Context: A low plasma level of high-density lipoprotein cholesterol (HDL-C) is a major risk factor for coronary heart disease (CHD). A secondary prevention study, the Veterans Affairs High-Density Lipoprotein Intervention...
8.
Kogai T, Curcio F, Hyman S, Cornford E, Brent G, Hershman J
J Endocrinol . 2000 Oct; 167(1):125-35. PMID: 11018760
Iodide uptake by the sodium/iodide symporter (NIS) in thyrocytes is essential for thyroid hormone production. Reduced NIS activity has been reported in thyroid diseases, including thyroid cancer and congenital hypothyroidism....
9.
Singh N, Singh P, Hershman J
JAMA . 2000 Jun; 283(21):2822-5. PMID: 10838651
Context: The effect of calcium carbonate on the absorption of levothyroxine has not been studied systematically. Such a potential drug interaction merits investigation because concurrent treatment with both drugs is...
10.
Hershman J
Thyroid . 1999 Aug; 9(7):653-7. PMID: 10447009
There is abundant evidence that human chorionic gonadotropin (hCG) is a weak thyrotropin (TSH) agonist. In FRTL-5 rat thyroid cells, hCG increases cyclic adenosine monophosphate (cAMP), iodide transport, and cell...