J M Freyssinet
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Explore the profile of J M Freyssinet including associated specialties, affiliations and a list of published articles.
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88
Citations
1517
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Recent Articles
1.
Satta N, Toti F, Fressinaud E, Meyer D, Freyssinet J
Platelets
. 2010 Mar;
8(2-3):117-24.
PMID: 20297932
Anionic phospholipids, chiefly phosphatidylserine, are essential for the assembly of the characteristic enzyme complexes of the blood coagulation cascade at the surface of stimulated platelets and derived microparticles. In the...
2.
Morel O, Jesel L, Freyssinet J, Toti F
Thromb J
. 2005 Oct;
3:15.
PMID: 16219103
Circulating procoagulant microparticles (MP) are pathogenic markers of enhanced coagulability associated to a variety of disorders and released from stimulated vascular cells. When derived from endothelial cells, MP were found...
3.
Morel O, Hugel B, Jesel L, Zobairi F, Bareiss P, Freyssinet J, et al.
Arch Mal Coeur Vaiss
. 2005 Jul;
97(10):1006-12.
PMID: 16008179
Endothelial apoptosis and platelet activation play a key role in atherothrombotic event. These two mechanisms resulting membrane thickening leading to procoagulant microparticle (MP) liberation into the blood stream. In the...
4.
[The significance of circulating microparticles in physiology, inflammatory and thrombotic diseases]
Morel O, Morel N, Hugel B, Jesel L, Vinzio S, Goichot B, et al.
Rev Med Interne
. 2005 Jun;
26(10):791-801.
PMID: 15936118
Background: In multicellular organisms, apoptosis and subsequent microparticle shedding play a key role in homeostasis. Having long been considered as << cellular dust >>, microparticles released in biological fluids upon...
5.
Morel O, Ohlmann P, Morel N, Jesel L, Bareiss P, Freyssinet J, et al.
Arch Mal Coeur Vaiss
. 2005 Apr;
98(3):226-35.
PMID: 15816326
Microparticles are membrane fragments liberated by activated or apoptopic cells. Thought for a long time to be cellular debris with no specific biologic function, in the vascular compartment they are...
6.
Jy W, Horstman L, Jimenez J, Ahn Y, Biro E, Nieuwland R, et al.
J Thromb Haemost
. 2004 Oct;
2(10):1842-51.
PMID: 15456497
No abstract available.
7.
Morel O, Jesel L, Chauvin M, Freyssinet J, Toti F
J Thromb Haemost
. 2003 Dec;
1(12):2685-7.
PMID: 14675110
No abstract available.
8.
Martinez M, Freyssinet J
BMC Cell Biol
. 2001 Nov;
2:20.
PMID: 11701087
Background: During apoptosis, Ca2+-dependent events participate in the regulation of intracellular and morphological changes including phosphatidylserine exposure in the exoplasmic leaflet of the cell plasma membrane. The occurrence of phosphatidylserine...
9.
Rossig L, Hoffmann J, Hugel B, Mallat Z, Haase A, Freyssinet J, et al.
Circulation
. 2001 Oct;
104(18):2182-7.
PMID: 11684628
Background: Proinflammatory cytokines like tumor necrosis factor-alpha and oxidative stress induce apoptotic cell death in endothelial cells (ECs). Systemic inflammation and increased oxidative stress in congestive heart failure (CHF) coincide...
10.
Lieby P, Soley A, Levallois H, Hugel B, Freyssinet J, Cerutti M, et al.
Blood
. 2001 Jun;
97(12):3820-8.
PMID: 11389022
The mechanism underlying the prothrombotic state that characterizes the primary antiphospholipid syndrome proves to be difficult to define mainly because of the variety of the phospholipid and protein targets of...