J Licht
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Explore the profile of J Licht including associated specialties, affiliations and a list of published articles.
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21
Citations
349
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Recent Articles
11.
Koken M, Daniel M, Gianni M, Zelent A, Licht J, Buzyn A, et al.
Oncogene
. 1999 Feb;
18(4):1113-8.
PMID: 10023688
Primary blasts of a t(11;17)(q23;q21) acute promyelocytic leukaemia (APL) patient were analysed with respect to retinoic acid (RA) and arsenic trioxide (As2O3) sensitivity as well as PLZF/RARalpha status. Although RA...
12.
Carroquino M, Galson S, Licht J, Amler R, Perera F, Claxton L, et al.
Environ Health Perspect
. 1998 Jul;
106 Suppl 3:867-73.
PMID: 9646050
On 15-16 September 1997, the U.S. Environmental Protection Agency sponsored the Conference on Preventable Causes of Cancer in Children. The conference was convened to examine rising trends in reported incidence...
13.
Koken M, Reid A, Quignon F, Chelbi-Alix M, Davies J, Kabarowski J, et al.
Proc Natl Acad Sci U S A
. 1997 Sep;
94(19):10255-60.
PMID: 9294197
In acute promyelocytic leukemia (APL), the typical t(15;17) and the rare t(11;17) translocations express, respectively, the PML/RARalpha and PLZF/RARalpha fusion proteins (where RARalpha is retinoic acid receptor alpha). Herein, we...
14.
Holmes G, Boterashvili S, English M, Wainwright B, Licht J, Little M
Biochem Biophys Res Commun
. 1997 Apr;
233(3):723-8.
PMID: 9168922
Patients with Denys-Drash syndrome (DDS) have been shown to be constitutionally heterozygous for mutations of the WT1 gene. Almost all DDS mutations inactivate or remove the DNA-binding zinc finger region...
15.
Dong S, Zhu J, Reid A, Strutt P, Guidez F, Zhong H, et al.
Proc Natl Acad Sci U S A
. 1996 Apr;
93(8):3624-9.
PMID: 8622986
Promyelocytic leukemia zinc finger-retinoic acid receptor a (PLZF-RARalpha), a fusion receptor generated as a result of a variant t(11;17) chromosomal translocation that occurs in a small subset of acute promyelocytic...
16.
Reid A, Gould A, Brand N, Cook M, Strutt P, Li J, et al.
Blood
. 1995 Dec;
86(12):4544-52.
PMID: 8541544
The PLZF gene was discovered by studying a rearrangement of the RAR alpha locus in a patient with acute promyelocytic leukemia and a t(11;17) chromosomal translocation. To understand further the...
17.
Cook M, Gould A, Brand N, Davies J, Strutt P, Shaknovich R, et al.
Proc Natl Acad Sci U S A
. 1995 Mar;
92(6):2249-53.
PMID: 7892256
To investigate the potential biological role(s) of the PLZF gene, discovered as a fusion with the RARA locus in a patient with acute promyelocytic leukemia harboring a t(11;17) chromosomal translocation,...
18.
Weinstein J, Myers T, Buolamwini J, Raghavan K, van Osdol W, Licht J, et al.
Stem Cells
. 1994 Jan;
12(1):13-22.
PMID: 8142917
The National Cancer Institute's drug discovery program screens more than 20,000 chemical compounds and natural products a year for activity against a panel of 60 tumor cell lines in vitro....
19.
Licht J, Gally D, Henderson T, Young K, Cooper S
Res Microbiol
. 1993 Jul;
144(6):423-33.
PMID: 8190989
The effects of mecillinam, ampicillin and cephalexin on peptidoglycan synthesis in Salmonella typhimurium 2616 have been studied at equivalent concentrations or "isoactivities". Using antibiotics at isoactivities allows a direct comparison...
20.
Seiden M, ODonnell W, Weinblatt M, Licht J
Bone Marrow Transplant
. 1990 Nov;
6(5):345-7.
PMID: 2291997
We report an unusual vasculitic syndrome in a long-term survivor of autologous bone marrow transplant. Clinical and pathologic studies revealed a cutaneous and pulmonary leukocytoclastic vasculitis complicated by recurrent pulmonary...