J L Rapoport
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Explore the profile of J L Rapoport including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Addington A, Gauthier J, Piton A, Hamdan F, Raymond A, Gogtay N, et al.
Mol Psychiatry
. 2010 May;
16(3):238-9.
PMID: 20479756
No abstract available.
12.
Eckstrand K, Addington A, Stromberg T, Merriman B, Miller R, Gochman P, et al.
Mol Psychiatry
. 2008 Sep;
13(10):910-1.
PMID: 18800051
No abstract available.
13.
Shaw P, Eckstrand K, Sharp W, Blumenthal J, Lerch J, Greenstein D, et al.
Proc Natl Acad Sci U S A
. 2007 Nov;
104(49):19649-54.
PMID: 18024590
There is controversy over the nature of the disturbance in brain development that underpins attention-deficit/hyperactivity disorder (ADHD). In particular, it is unclear whether the disorder results from a delay in...
14.
Gornick M, Addington A, Shaw P, Bobb A, Sharp W, Greenstein D, et al.
Am J Med Genet B Neuropsychiatr Genet
. 2006 Dec;
144B(3):379-82.
PMID: 17171657
Polymorphisms of the dopamine receptor D4 gene DRD4, 11p15.5, have previously been associated with attention-deficit/hyperactivity disorder (ADHD) [Bobb et al., 2005; Am J Med Genet B Neuropsychiatr Genet 132:109-125; Faraone...
15.
Addington A, Gornick M, Shaw P, Seal J, Gogtay N, Greenstein D, et al.
Mol Psychiatry
. 2006 Oct;
12(2):195-205.
PMID: 17033632
Childhood-onset schizophrenia (COS), defined as onset of psychosis by the age of 12, is a rare and malignant form of the illness, which may have more salient genetic influence. Since...
16.
Seal J, Gornick M, Gogtay N, Shaw P, Greenstein D, Coffey M, et al.
J Med Genet
. 2006 Jun;
43(11):887-92.
PMID: 16763011
Schizophrenia is a severe mental disorder affecting approximately 1% of the world's population. Although the aetiology of schizophrenia is complex and multifactorial, with estimated heritabilities as high as 80%, genetic...
17.
Gornick M, Addington A, Sporn A, Gogtay N, Greenstein D, Lenane M, et al.
J Autism Dev Disord
. 2005 Nov;
35(6):831-8.
PMID: 16283082
Straub et al. (2002) recently identified the 6p22.3 gene dysbindin (DTNBP1) through positional cloning as a schizophrenia susceptibility gene. We studied a rare cohort of 102 children with onset of...
18.
Rapoport J, Addington A, Frangou S, Psych M
Mol Psychiatry
. 2005 Feb;
10(5):434-49.
PMID: 15700048
Neurodevelopmental models of schizophrenia that identify longitudinal precursors of illness have been of great heuristic importance focusing most etiologic research over the past two decades. These models have varied considerably...
19.
Addington A, Gornick M, Duckworth J, Sporn A, Gogtay N, Bobb A, et al.
Mol Psychiatry
. 2004 Oct;
10(6):581-8.
PMID: 15505639
Postmortem brain studies have shown deficits in the cortical gamma-aminobutyric acid (GABA) system in schizophrenic individuals. Expression studies have shown a decrease in the major GABA-synthesizing enzyme (glutamic acid decarboxylase...
20.
Arcos-Burgos M, Castellanos F, Konecki D, Lopera F, Pineda D, Palacio J, et al.
Mol Psychiatry
. 2004 Apr;
9(3):252-9.
PMID: 15094785
Association/linkage between dopamine D4 receptor (DRD4) polymorphisms and attention-deficit/hyperactivity disorder (ADHD) has been suggested by case-control- and nuclear-family-based studies. Here, we present a candidate gene analysis for DRD4 using 14...