J L Lordan
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Explore the profile of J L Lordan including associated specialties, affiliations and a list of published articles.
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25
Citations
624
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Recent Articles
1.
Stephenson D, Perry A, Appleby M, Lee D, Davison J, Johnston A, et al.
BMC Pulm Med
. 2019 Jan;
19(1):19.
PMID: 30665395
Background: RGM medium is an agar-based, selective culture medium designed for the isolation of nontuberculous mycobacteria (NTM) from the sputum of patients with cystic fibrosis (CF). We evaluated RGM medium...
2.
McDonnell M, OToole D, Ward C, Pearson J, Lordan J, De Soyza A, et al.
Respir Med
. 2018 Jul;
141:132-143.
PMID: 30053958
Gastro-oesophageal reflux disease (GORD) is a common comorbidity in bronchiectasis, and is often associated with poorer outcomes. The cause and effect relationship between GORD and bronchiectasis has not yet been...
3.
Sithamparanathan S, Thirugnanasothy L, Morley K, Fisher A, Lordan J, Meachery G, et al.
Transplant Proc
. 2016 Dec;
48(10):3387-3392.
PMID: 27931586
Background: Methotrexate (MTX) is potential change in immunosuppression after lung transplantation that may help to slow down the decline in lung function in bronchiolitis obliterans syndrome (BOS). Methods: We sought...
4.
McDonnell M, Anwar G, Rutherford R, De Soyza A, Worthy S, Corris P, et al.
Respir Med
. 2014 Jul;
108(8):1127-33.
PMID: 24986480
Introduction: Idiopathic bronchiectasis is a poorly defined disease characterised by persistent inflammation, infection and progressive lung damage. Natural killer (NK) cells provide a major defense against infection, through the interaction...
5.
McDonnell M, Ward C, Lordan J, Rutherford R
QJM
. 2013 Jun;
106(8):709-15.
PMID: 23728208
Bronchiectasis is a chronic debilitating condition with considerable phenotypic diversity. A vicious cycle of infection and inflammation exists in damaged airways with patients suffering from persistent cough, purulent sputum production,...
6.
Yates B, Murphy D, Fisher A, Gould F, Lordan J, Dark J, et al.
BMJ Case Rep
. 2011 Jun;
2009.
PMID: 21686410
In the present study, 4 patients with cystic fibrosis undergoing lung transplantation (from a total of 137) who developed fulminant pseudomembranous colitis are described. Initial presentation was variable and the...
7.
Lee W, Kirkham N, Johnson M, Lordan J, Fisher A, Peacock A
Eur Respir J
. 2011 Feb;
37(2):472-4.
PMID: 21282815
No abstract available.
8.
Brodlie M, McKean M, Johnson G, Anderson A, Hilkens C, Fisher A, et al.
Eur Respir J
. 2010 Nov;
37(6):1378-85.
PMID: 21109552
Interleukin (IL)-17 is pivotal in orchestrating the activity of neutrophils. Neutrophilic inflammation is the dominant pathology in cystic fibrosis (CF) lung disease. We investigated IL-17 protein expression in the lower...
9.
Borthwick L, McIlroy E, Gorowiec M, Brodlie M, Johnson G, Ward C, et al.
Am J Transplant
. 2010 Jan;
10(3):498-509.
PMID: 20055810
Epithelial to mesenchymal transition (EMT) has been implicated in the pathogenesis of obliterative bronchiolitis (OB) after lung transplant. Although TNF-alpha accentuates TGF-beta1 driven EMT in primary human bronchial epithelial cells...
10.
Borthwick L, Parker S, Brougham K, Johnson G, Gorowiec M, Ward C, et al.
Thorax
. 2009 Feb;
64(9):770-7.
PMID: 19213777
Background: Aberrant epithelial repair is a key event in the airway remodelling which characterises obliterative bronchiolitis (OB) in the transplanted lung. The potential for airway epithelium from lung transplant recipients...