J L Guerquin-Kern
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Explore the profile of J L Guerquin-Kern including associated specialties, affiliations and a list of published articles.
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17
Citations
201
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Recent Articles
1.
Houari S, Picard E, Wurtz T, Vennat E, Roubier N, Wu T, et al.
J Dent Res
. 2019 Jul;
98(9):994-1001.
PMID: 31329045
Enamel formation and quality are dependent on environmental conditions, including exposure to fluoride, which is a widespread natural element. Fluoride is routinely used to prevent caries. However, when absorbed in...
2.
Elbast M, Wu T, Guiraud-Vitaux F, Guerquin-Kern J, Petiet A, Hindie E, et al.
Cell Mol Biol (Noisy-le-grand)
. 2008 Feb;
53 Suppl:OL1018-24.
PMID: 18184480
The most significant impact of the Chernobyl accident is the increased incidence of thyroid cancers among children. In order to accurately estimate the radiation dose provided by radioiodines, it is...
3.
Quintana C, Bellefqih S, Laval J, Guerquin-Kern J, Wu T, Avila J, et al.
J Struct Biol
. 2005 Dec;
153(1):42-54.
PMID: 16364657
Previous studies of the structure of core nanocrystals of ferritin (Ft) in the brains of patients with Alzheimer's disease (AD) have shown differences in the mineral compound in comparison with...
4.
Guerquin-Kern J, Volk A, Chenu E, Monneret C, Florent J, Carrez D, et al.
NMR Biomed
. 2000 Aug;
13(5):306-10.
PMID: 10960921
A glucuro-conjugated carbamate derivative of 5-fluorouracil (5-FU), originally designed as a prodrug for antibody-directed enzyme prodrug therapy (ADEPT) application, has been used for direct in vivo observation of in situ...
5.
Dominguez H, ROLLIN C, Guyonvarch A, Guerquin-Kern J, Cocaign-Bousquet M, Lindley N
Eur J Biochem
. 1998 Jul;
254(1):96-102.
PMID: 9652400
Growth of Corynebacterium glutamicum on fructose was significantly less than that obtained on glucose, despite similar rates of substrate uptake. This was in part due to the production of overflow...
6.
Guerquin-Kern J, Coppey M, Carrez D, Brunet A, Nguyen C, Rivalle C, et al.
Microsc Res Tech
. 1997 Feb;
36(4):287-95.
PMID: 9140928
Low light level fluorescence microscopy studies have been carried out on MCF7-P human mammary tumor cells to localize the intracellular distribution of two new anticancer drugs, Pazelliptine and Intoplicine, which...
7.
ROLLIN C, Morgant V, Guyonvarch A, Guerquin-Kern J
Eur J Biochem
. 1995 Jan;
227(1-2):488-93.
PMID: 7851427
Coryneform bacteria are widely used to produce amino acids, in particularly glutamic acid, by fermentation. To study the metabolic fate of glucose as the carbon source, we developed a method...
8.
Trudel M, Saadane N, Garel M, Bardakdjian-Michau J, Blouquit Y, Guerquin-Kern J, et al.
EMBO J
. 1991 Nov;
10(11):3157-65.
PMID: 1915288
In order to obtain a transgenic mouse model of sickle cell disease, we have synthesized a novel human beta-globin gene, beta SAD, designed to increase the polymerization of the transgenic...
9.
Guerquin-Kern J, Leteurtre F, Croisy A, Lhoste J
Cancer Res
. 1991 Oct;
51(20):5770-3.
PMID: 1913695
Multinuclear nuclear magnetic resonance spectroscopy was used to follow the metabolism and kinetics of 5-fluorouracil (5FU) after i.v. administration at a dose of 100 mg/kg on Wistar rats. 31P spectra...
10.
Allavena C, Guerquin-Kern J, Lhoste J
Radiother Oncol
. 1991 May;
21(1):48-52.
PMID: 1906625
The energy metabolism of tumors in rats was investigated by in vivo 31P-NMR spectroscopy. The effects of radiotherapy, chemotherapy or radiotherapy combined with 5-fluorouracil (5-FU) chemotherapy were evaluated by observing...